PMID: 16527007Mar 11, 2006Paper

The use of zoledronic acid for Paget's disease of bone

Current Osteoporosis Reports
Michael Maricic

Abstract

Paget's disease of bone is a common skeletal disorder of the elderly that often results in significant morbidity and disability. Although there are a number of oral bisphosphonates currently available for treatment, normalization of biochemical markers of bone turnover with these agents is rarely accomplished due to difficulty with administration, adherence, and possibly resistance to individual bisphosphonates. This paper will focus on zoledronic acid, a potent and easily administered intravenous bisphosphonate that appears to result in a higher percentage of patients with normalization of markers of bone turnover and results in improvements in quality of life in patients with Paget's disease of bone.

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Citations

Jan 5, 2011·Proceedings of the National Academy of Sciences of the United States of America·Tali SharonAsaf Gilboa
Apr 3, 2010·Brain : a Journal of Neurology·Fraser MiltonAdam Z J Zeman
Feb 17, 2007·Seminars in Arthritis and Rheumatism·Stuart L Silverman, Michael Maricic

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