The usefulness of dipyridamole thallium-201 single photon emission computed tomography for predicting perioperative cardiac events in patients undergoing non-cardiac vascular surgery

Annals of Nuclear Medicine
Tao ChenKouji Masuda

Abstract

The aim of this study was to evaluate the usefulness of dipyridamole Tl-201 myocardium single photon emission computed tomography (201Tl-SPECT) for predicting perioperative cardiac events in patients with arteriosclerosis obliterans (ASO) and abdominal aortic aneurysm (AAA) undergoing non-cardiac vascular surgery. Preoperative dipyridamole 201Tl-SPECT imaging in association with clinical risk assessment was performed in 224 consecutive patients (97 ASO and 127 AAA). The patients were classified into three groups, including low-risk (n = 173, 77%), intermediate-risk (n = 39, 18%), and high-risk (n = 12, 5%) groups according to the clinical risk stratification. The prevalence of reversible Tl-201 defect was significantly higher in the high-risk group than that in the low-risk group (83% vs. 14%, p < 0.001). In 180 patients who underwent vascular surgery, 9 patients (5.0%) had perioperative cardiac events, including heart failure (n = 1), unstable angina (n = 2), and other cardiac events such as arrhythmias (n = 6). The clinical variables including the clinical risk stratification did not significantly correlate with the perioperative cardiac events. In contrast, the reversible defect on 201Tl-SPECT was the only variable to predic...Continue Reading

References

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Citations

Sep 25, 2008·Circulation Journal : Official Journal of the Japanese Circulation Society·Tomotaka KasamatsuAtsushi Kubo
Apr 26, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Katsufumi HarafujiAkira Yamashina
Oct 22, 2008·The Journal of Physiological Sciences : JPS·Eun Bo ShimYung E Earm
Dec 22, 2005·Anesthesia and Analgesia·W Scott BeattieD Norman Buckley

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