The utility of assessing the gross appearances of FNA specimens

Cytopathology : Official Journal of the British Society for Clinical Cytology
Frederick MayallK McAnulty

Abstract

Ideally, fine needle aspiration (FNA) cytology should be performed with near-patient assessment of the adequacy of the specimen by a cytopathologist. However, this is often not feasible. A cruder alternative is for the FNA practitioner to examine the gross appearances of the specimen and to try to predict the its quality. This study set out to determine the value of this approach. The study was conducted in tertiary public hospitals in New Zealand and the UK. FNA gross material grading was performed by a variety of pathologists on FNA samples taken using manual guidance and image guidance. The FNA gross material grade was compared with the findings on microscopic examination. Nine out of 123 FNA samples were assessed as Grade 1 (unlikely to contain diagnostic material). All were subsequently reported as having insufficient diagnostic tissue on microscopic examination. Forty-two of the FNA samples were assessed as Grade 2 (possibly contains diagnostic material) and 46 as Grade 3 (probably contains diagnostic material). None from either of these grades was reported as showing insufficient diagnostic material on microscopic examination. Twenty-six cases were reported as Grade 4 (material suggesting a specific diagnosis). None of t...Continue Reading

References

Nov 3, 1998·Journal of Clinical Pathology·F MayallA Darlington
Sep 27, 2008·Journal of Clinical Pathology·F G MayallA Darlington

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Citations

Jun 21, 2014·Endoscopic Ultrasound·Shantel Hébert-Magee
Jan 27, 2016·Journal of Cytology·Amit Kumar ChowhanAsha Thotta
Apr 6, 2011·Cytopathology : Official Journal of the British Society for Clinical Cytology·A K ChowhanB V Phaneendra
Nov 21, 2013·Korean Journal of Pathology·Jennifer A CollinsMatthew T Olson
Oct 30, 2013·Annals of the Royal College of Surgeons of England·V M ReddyS A Hickey
Jun 17, 2020·Diagnostic Cytopathology·José Cândido Caldeira Xavier-JúniorNeivio José Mattar

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