The utility of computed tomography scans in predicting suboptimal cytoreductive surgery in women with advanced ovarian carcinoma

Cancer
Sean C DowdyWilliam A Cliby

Abstract

Computed tomography (CT) scans of the abdomen and pelvis may predict which patients with ovarian carcinoma can undergo optimal cytoreduction at primary surgery. Previous studies have demonstrated that patients with ovarian carcinoma had optimal cytoreduction rates ranging from 50-60%. The authors sought to determine whether these findings applied to a surgical practice with a higher rate of optimal debulking. A predictive model using CT scanning and CA 125 values would allow the authors to determine which patients would be more appropriately treated with neoadjuvant chemotherapy. Preoperative CT scans for patients with Stage III/IV ovarian carcinoma (according to the staging system of the International Federation of Gynecology and Obstetrics) who were treated between 1996 and 2001 were evaluated retrospectively by 2 radiologists for 17 criteria evaluating the extent of disease. Clinical data were extracted from medical records. Residual tumors measuring > or = 1 cm were considered suboptimal. Logistic regression was used to evaluate which criteria correlated with optimal cytoreduction. Eighty-seven patients were identified retrospectively who met entry criteria and had preoperative CT scans of sufficient diagnostic quality. Six...Continue Reading

References

Jun 1, 1990·Gynecologic Oncology·J T ChambersP E Schwartz
Jun 1, 1986·Obstetrics and Gynecology·A P HeintzL D Lagasse
Oct 1, 1995·AJR. American Journal of Roentgenology·J I MeyerR C Zepp
Apr 1, 1994·Gynecologic Oncology·P E SchwartzR Makuch
Jan 1, 1993·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·B E NelsonP E Schwartz
Jan 16, 1999·Gynecologic Oncology·P E SchwartzR P Thiel
Mar 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Robert E BristowF J Montz
Apr 6, 2002·Journal of Cancer Research and Clinical Oncology·J HuoberD Wallwiener
Feb 6, 2003·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael J Thun
Mar 27, 2003·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·S MemarzadehR Farias-Eisner

❮ Previous
Next ❯

Citations

Apr 9, 2010·Archives of Gynecology and Obstetrics·Hyuck Jae ChoiSang-Yoon Park
Feb 25, 2011·Archives of Gynecology and Obstetrics·Kazuko FujwaraMasatoshi Hori
Oct 21, 2009·Current Oncology Reports·Peter E Schwartz
Dec 30, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S Kang, S-Y Park
Feb 16, 2005·Current Opinion in Obstetrics & Gynecology·Roman Rouzier, Christophe Pomel
Feb 22, 2012·Clinical Obstetrics and Gynecology·Ritu Salani, Robert E Bristow
Oct 15, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Ur MetserSarah Ferguson
Oct 15, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Caitlin StashwickMichael Greg Kelly
Jan 9, 2013·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Ulrike DehaeckJanice S Kwon
Nov 22, 2013·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Seung-Hyuk ShimJoo-Hyun Nam
Sep 18, 2007·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·A H M M AritsA C Voogd
Nov 8, 2007·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·A E BlandP T Taylor
Mar 8, 2014·Women's Health·Martin PölcherDennis S Chi
Jul 16, 2014·Current Opinion in Oncology·Andrea G Rockall
Aug 3, 2011·Expert Review of Anticancer Therapy·Takashi Onda, Hiroyuki Yoshikawa
Oct 16, 2014·Gynecologic Oncology·John O SchorgeRichard T Penson
Jan 9, 2016·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Matthew D RisiArthur F Gmitro
Apr 29, 2015·Gynecologic Oncology·Jo Marie Tran JancoJamie N Bakkum-Gamez
Dec 12, 2012·Gynecologic Oncology·Roberto AngioliPierluigi Benedetti-Panici
Sep 25, 2010·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·C FotopoulouJ Sehouli
Oct 12, 2010·Gynecologic Oncology·Giovanni D AlettiWilliam A Cliby
Mar 31, 2009·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·O GemerO Lavie
Jun 7, 2007·Mayo Clinic Proceedings·Giovanni D AlettiLynn C Hartmann
Dec 2, 2008·Gynecologic Oncology·Dennis S Chi, Peter E Schwartz
Nov 29, 2015·Magnetic Resonance Imaging Clinics of North America·Nandita M deSouzaSusan Freeman
Dec 24, 2005·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A C TestaG Ferrandina
Nov 5, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Mari B ElstrandClaes G Tropé
Apr 1, 2009·Seminars in Oncology·Carolyn Krasner, Linda Duska
Jul 4, 2007·Surgical Oncology Clinics of North America·Donald L Klippenstein, Dominick M Lamonica
Feb 21, 2006·Gynecologic Oncology·Robert E Bristow
Dec 6, 2005·Gynecologic Oncology·Roberto AngioliPierluigi Benedetti Panici

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.