The utility of fFN for the prediction of preterm birth in twin gestations

Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN
R J RuizCharles E L Brown

Abstract

To determine the sensitivity, specificity, and positive predictive value (PPV) of fetal fibronectin (fFN) and to determine its usefulness, in conjunction with selected other clinical assessment measures, in the prediction of preterm birth for women with twin gestations. A prospective, descriptive, longitudinal design. An obstetrical high-risk clinic that received patient referrals from several surrounding communities in central Texas. Forty-eight women identified with twin gestations prior to the 22nd week of pregnancy; primarily of Hispanic ethnicity. A substantial number of outcome variables were assessed in this study. In the present report, data derived from weekly assessments for the identification of the presence of fFN, the diagnosis of bacterial vaginosis, and the measurement of cervical length were reviewed for their relationship to prematurity, birth weight, birth weight discordancy and placental chorionicity. The relative risk of birth prior to 35 weeks gestation, fetal death, or discordance of twin birth weights of greater than 20% was 2.22 (CI: 1.09, 4.55, P < 0.015) when fFN was found to be positive at any weekly testing after 22 to 24 weeks gestation (sensitivity 76.82%, specificity 58.33%, PPV 66.7%). The presen...Continue Reading

References

Sep 5, 1991·The New England Journal of Medicine·C J LockwoodT J Garite
Aug 1, 1991·American Journal of Obstetrics and Gynecology·R B NewmanM C Miller
Mar 1, 1982·British Journal of Obstetrics and Gynaecology·M C HoultonR H Philpott
Nov 1, 1995·American Journal of Obstetrics and Gynecology·T ColtonT Heeren
Aug 1, 1995·American Journal of Obstetrics and Gynecology·P J MeisK A Johns
Mar 1, 1995·British Journal of Obstetrics and Gynaecology·P HellemansP Verdonk
Oct 1, 1993·American Journal of Obstetrics and Gynecology·C J LockwoodR L Berkowitz
Jan 1, 1994·American Journal of Obstetrics and Gynecology·M P NageotteA E Senyei
May 1, 1996·Obstetrics and Gynecology·J C MorrisonB N McLaughlin
Jun 1, 1996·American Journal of Obstetrics and Gynecology·B M MercerJ Roberts
Jul 1, 1997·American Journal of Obstetrics and Gynecology·A M PeacemanM Pietrantoni
Jan 7, 1998·Brain, Behavior, and Immunity·S GennaroS D Douglas
Feb 12, 1998·Journal of Reproductive Immunology·D J Dudley
May 16, 1998·Epidemiology·G S BerkowitzD A Savitz
Jul 2, 1998·Obstetrics and Gynecology·G FaronW D Fraser
Sep 28, 1998·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·T OliveiraL Camano
Mar 17, 1999·American Journal of Obstetrics and Gynecology·G M JoffeP Shelburne
May 18, 1999·American Journal of Obstetrics and Gynecology·H LeitichP Husslein
Oct 8, 1999·São Paulo Medical Journal = Revista Paulista De Medicina·T A OliveiraL Camano
Nov 27, 1999·Obstetrics and Gynecology·L M HollierK J Leveno
Dec 1, 1999·European Journal of Obstetrics, Gynecology, and Reproductive Biology·M MizrahiM Mazor
Jan 29, 2000·American Journal of Obstetrics and Gynecology·E B St JohnR L Goldenberg
Jul 13, 2000·JAMA : the Journal of the American Medical Association·M D KoganE Papiernik
Feb 27, 2001·Journal of the Society for Gynecologic Investigation·J D IamsG Weiss
Mar 27, 2001·Acta Obstetricia Et Gynecologica Scandinavica·L Sperling, A Tabor
Mar 30, 2001·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·R J RuizA B Johnston
Sep 25, 2001·American Journal of Obstetrics and Gynecology·R L GoldenbergUNKNOWN Maternal-Fetal Medicine Units Network
Jan 19, 2002·The Journal of Maternal-fetal Medicine·A SullivanA J Satin
Mar 21, 2002·American Journal of Obstetrics and Gynecology·Johanne DubéB Anthony Armson
Mar 27, 2002·Current Opinion in Obstetrics & Gynecology·Alec Welsh, Kypros Nicolaides
Oct 29, 2002·Seminars in Neonatology : SN·Roberto RomeroKarim Kalache

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Citations

Jan 24, 2007·Best Practice & Research. Clinical Obstetrics & Gynaecology·Harald Leitich, Herbert Kiss
Apr 6, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Nesa AsnafiSarah Dadvar
Jun 20, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Gilles FaronLeonardo Gucciardo
May 2, 2007·Obstetrics and Gynecology·Emily SingerGlenn Markenson
May 17, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Lene Hee
Nov 12, 2010·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Agustín Conde-Agudelo, Roberto Romero
May 24, 2020·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Shemoon MarleenShakila Thangaratinam
Jul 30, 2014·American Journal of Obstetrics and Gynecology·Agustin Conde-Agudelo, Roberto Romero
Feb 15, 2005·Prenatal Diagnosis

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