PMID: 9542222May 16, 1998Paper

The utility of gammagraphy with Tc 99-labelled dimercaptosuccinic acid (DMSA) in the protocol for studying urinary infection in a 2nd-level hospital

Anales españoles de pediatría
J L Matesanz PérezS Ballesteros García

Abstract

Not all hospitals in our country have their own nuclear medicine laboratory. Most small and medium size hospitals must arrange their radioisotope studies with private clinics. The objective of this study was to assess if a single DMSA scan performed after an acute infection in a group of patients chosen according to certain risk criteria would allow the selection of those who run the risk of progressive renal damage. A descriptive and retrospective study of the clinical records of 65 patients under 14 years of age with urinary tract infection (UTI) seen at our institution between 1994 and 1995 and on whom a DMSA scan had been performed was carried out. The study groups was formed by the fifteen children with scintigraphic findings compatible with renal scarring. The fifty children with normal DMSA scans were used as controls. Renal scarring was found more often in patients over one year of age (p < 0.05), in those with reinfections (p < 0.001) and in those kidneys with grade III vesicoureteral reflux (VUR, p < 0.05). The most severe lesions, with reduction of renal size, shape abnormalities and diminished uptake of the tracer were found together with VUR. The renal sonogram performed during the acute stage of the UTI was able t...Continue Reading

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