The utility of metaiodobenzylguanidine single photon emission computed tomography/computed tomography (MIBG SPECT/CT) for the diagnosis of pheochromocytoma

Annals of Surgical Oncology
Goswin Y Meyer-RochowStan B Sidhu

Abstract

The enhancement of metaiodobenzylguanidine single photon emission computed tomography (MIBG SPECT) imaging through the addition of CT images fused with SPECT data (coregistered MIBG SPECT/CT imaging) is new technology that allows direct correlation of anatomical and functional information. We hypothesized that MIBG SPECT/CT imaging would provide additional information and improve diagnostic confidence for the radiological localization of a pheochromocytoma, in particular for patients at high risk of multifocal or recurrent disease. A retrospective study of all patients investigated by MIBG SPECT/CT at our institution from 2006 to 2008 for a suspected pheochromocytoma was performed. Each case was compared with conventional radiological investigations to determine whether MIBG SPECT/CT was able to improve diagnostic confidence and provide additional diagnostic information compared with conventional imaging alone. Twenty-two patients had MIBG SPECT/CT imaging for a suspected pheochromocytoma. Fourteen patients had positive MIBG SPECT/CT imaging results correlating with imaging by CT or magnetic resonance imaging in all cases. In six cases, MIBG SPECT/CT provided additional information that altered the original radiological diagnos...Continue Reading

References

Jan 1, 1992·The Journal of Urology·R K WhalenG H Daniels
Jun 1, 1967·Annals of Internal Medicine·A M Lawrence
Mar 30, 1999·World Journal of Urology·M M WaltherW M Linehan
May 10, 2002·The New England Journal of Medicine·Hartmut P H NeumannUNKNOWN Freiburg-Warsaw-Columbus Pheochromocytoma Study Group
Oct 17, 2002·Annals of the New York Academy of Sciences·Barbro ErikssonBengt Långström
Feb 7, 2004·The Journal of Clinical Endocrinology and Metabolism·Ioannis Ilias, Karel Pacak
Jul 9, 2004·Annals of the New York Academy of Sciences·Ioannis Ilias, Karel Pacak
Jan 13, 2005·The Journal of Clinical Endocrinology and Metabolism·Laurence AmarPierre-François Plouin
Aug 16, 2005·The Medical Journal of Australia·Yaser AlderaziStan B Sidhu
Aug 23, 2005·Lancet·Jacques W M LendersKarel Pacak
Oct 7, 2005·Internal Medicine Journal·P J Roach, D L Bailey
Jun 10, 2006·Seminars in Nuclear Medicine·Vittoria RufiniRichard P Baum
Aug 17, 2006·The Journal of Clinical Endocrinology and Metabolism·Frederieke M BrouwersKarel Pacak
Oct 13, 2006·European Journal of Nuclear Medicine and Molecular Imaging·Klaus StrobelThomas F Hany
Nov 15, 2006·Annals of the New York Academy of Sciences·William M Manger
Jan 15, 2008·Annals of Surgical Oncology·David Yü GreenblattHerbert Chen
Mar 22, 2008·AJR. American Journal of Roentgenology·Katia RozovskyMartine Klein
May 21, 2008·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·G EisenhoferK Pacak
Jul 30, 2008·Langenbeck's Archives of Surgery·Radu MihaiGreg Sadler
Feb 27, 2009·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M D GrossD Rubello
Jun 9, 2009·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Run Yu
Aug 20, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Gregory A WisemanArnold F Jacobson

❮ Previous
Next ❯

Citations

Aug 31, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Gad Abikhzer, Zohar Keidar
Jan 25, 2013·AJR. American Journal of Roentgenology·Katherine LeungGavin Low
Jul 21, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Emilio BombardieriUNKNOWN European Association for Nuclear Medicine
Nov 30, 2011·Langenbeck's Archives of Surgery·Oliver GimmLaurent Brunaud
May 29, 2012·Clinical Radiology·K K WongD Rubello
Feb 7, 2012·Best Practice & Research. Clinical Endocrinology & Metabolism·S McDermottM A Blake
Feb 26, 2011·Endocrinology and Metabolism Clinics of North America·David L Bushnell, Richard P Baum
May 26, 2012·Journal of Surgical Oncology·Clara C Chen, Jorge A Carrasquillo
Nov 28, 2015·Surgical Oncology Clinics of North America·Colleen M Kiernan, Carmen C Solórzano
Oct 30, 2016·Revista española de medicina nuclear e imagen molecular·K K WongD Rubello
Oct 30, 2016·Revista española de medicina nuclear e imagen molecular·H BowlesS Vidal-Sicart
Apr 11, 2013·Current Opinion in Endocrinology, Diabetes, and Obesity·Subramanian KannanAmir H Hamrahian
Nov 13, 2013·Clinical Nuclear Medicine·Ingo EinspielerMarc E Martignoni
Jul 1, 2014·Endocrine Reviews·Ka Kit WongMilton D Gross
Jun 12, 2013·Clinical Nuclear Medicine·Chiara FuccioDomenico Rubello
Oct 23, 2018·Nuclear Medicine and Molecular Imaging·Daris TheerakulpisutCharoonsak Somboonporn
Jan 1, 2012·Hormones : International Journal of Endocrinology and Metabolism·Vittoria RufiniAlessandro Giordano

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Endocrinology
Robin P F DullaartKlaas P Koopmans
Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Alzheimer's Association
European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
K A Miles
© 2022 Meta ULC. All rights reserved