The utility of routine clinical 12-lead ECG in assessing eligibility for subcutaneous implantable cardioverter defibrillator

Computers in Biology and Medicine
Jason A ThomasLarisa G Tereshchenko

Abstract

The subcutaneous implantable cardioverter-defibrillator (S-ICD) is a life-saving device. Recording of a specialized 3-lead electrocardiogram (ECG) is required for S-ICD eligibility assessment. The goals of this study were: (1) evaluate the effect of ECG filtering on S-ICD eligibility, and (2) simplify S-ICD eligibility assessment by development of an S-ICD ineligibility prediction tool, which utilizes the widely available routine 12-lead ECG. Prospective cross-sectional study participants [n = 68; 54% male; 94% white, with wide ranges of age (18-81 y), body mass index (19-53), QRS duration (66-150 ms), and left ventricular ejection fraction (37-77%)] underwent 12-lead supine, 3-lead supine and standing ECG recording. All 3-lead ECG recordings were assessed using the standard S-ICD pre-implantation ECG morphology screening. Backward, stepwise, logistic regression was used to build a model for 12-lead prediction of S-ICD eligibility. Select electrocardiogram waves and complexes: QRS, R-, S, and T-amplitudes on all 12 leads, averaged QT interval, QRS duration, and R/T ratio in the lead with the largest T wave (R/Tmax) were included as predictors. The effect of ECG filtering on ECG morphology was evaluated. A total of 9 participant...Continue Reading

Associated Clinical Trials

Jul 6, 2017·Larisa Tereshchenko

References

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Citations

Aug 19, 2020·Circulation. Arrhythmia and Electrophysiology·Kazi T HaqLarisa G Tereshchenko
May 27, 2021·ESC Heart Failure·Linda WangLarisa G Tereshchenko
Jun 7, 2021·Journal of Electrocardiology·Jan WagnerJulia Köbe
Jun 15, 2021·ESC Heart Failure·Christos ZormpasDavid Duncker

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