PMID: 41605Dec 1, 1979

The utilization of hypnotics in chronic schizophrenics: some critical remarks

Biological Psychiatry
K JusP Fontaine

Abstract

Of 23 hospitalized chronic schizophrenic patients, all under neuroleptic medication, hypnotics taken previously for a long time could be totally withdrawn in 16 cases, and in 7 cases, the dosage was diminished by 30%, without any sleep impairment. The gradual reduction of hypnotics was accompanied by a shift of neuroleptic dosage to the evening and bedtime, with reduction of the morning and midday dose, without change of the total daily dose. A significant improvement in the psychic state was observed in 16 patients after withdrawal of the hypnotic; 7 patients showed a slight improvement after reduction of the hypnotic. Monthly or bimonthly reassessment of insomnia in the hospitalized population of chronic schizophrenics is indispensable to avoid the deleterious effects and abuse of hypnotic drugs.

Related Concepts

Dose-Response Relationship, Drug
Polychemotherapy
Sedatives
Transient Insomnia
Schizophrenia
Schizophrenic Psychology
Sleep Stages
Withdrawal Symptoms
Antipsychotic Effect

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