The vacuole versus the lysosome: when size matters

Autophagy
Daniel J Klionsky, Eeva-Liisa Eskelinen

Abstract

The morphometric examination of autophagic bodies provides useful information about the mechanism and magnitude of macroautophagy, and yeast researchers frequently utilize various measurements of these structures as part of their quantification of the process. The utility of this approach, however, has led to the common misconception that autophagic bodies can be found in the mammalian lysosome, which is generally not correct.

References

Feb 20, 1967·Archiv für Mikrobiologie·P Matile, A Wiemken
May 1, 1968·Journal of General Microbiology·K J Indge
May 14, 2011·Autophagy·Eeva-Liisa EskelinenPer O Seglen

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Citations

Aug 23, 2018·The Journal of Biological Chemistry·David ColecchiaMario Chiariello
Jun 11, 2016·Biochemical Society Transactions·Carine de Marcos Lousa, Jurgen Denecke
Jun 6, 2020·Autophagy·Kiran PandeyCristina M Alberini
Apr 24, 2019·The Journal of Cell Biology·Fan ZhouNava Segev
Mar 7, 2019·Cell Cycle·Franziska KriegenburgClaudine Kraft
Sep 29, 2019·International Journal of Molecular Sciences·Sławomir BorekMałgorzata Pietrowska-Borek
Feb 13, 2020·Cell Discovery·Willa Wen-You Yim, Noboru Mizushima
Dec 9, 2020·Proceedings of the National Academy of Sciences of the United States of America·Ryan J SchulzeMark A McNiven
Feb 11, 2021·Cell Discovery·Willa Wen-You Yim, Noboru Mizushima
Jun 3, 2021·International Journal of Molecular Sciences·Kamila BuzunAnna Bielawska
Aug 21, 2021·Journal of Histotechnology·Cynthia G Trejo-IriarteNatalio García-Honduvilla
Sep 24, 2021·The Biochemical Journal·Charles B Trelford, Gianni M Di Guglielmo

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