The validity of hyperdense lumen sign in non-contrast chest CT scans in the detection of pulmonary thromboembolism.

The International Journal of Cardiovascular Imaging
Vincent R Tatco, Honorato H Piedad

Abstract

It is possible to identify high-attenuation clots in pulmonary thromboembolism using non-contrast computed tomography (CT) of the chest. Such detection may be crucial for timely initiation of appropriate therapy. This study was undertaken to determine the validity of the hyperdense lumen (high-attenuation clot) sign in unenhanced chest CT in detecting pulmonary thromboembolism. Non-contrast and contrast-enhanced CT images of the chest of 121 patients who had undergone standard CT pulmonary angiography (pulmonary CTA) were reviewed separately. The absence or presence of luminal hyperdensities within the pulmonary arteries in the non-contrast images was determined. The average CT attenuation differences between the high attenuation clots and pulmonary arteries were computed. Findings in the non-contrast images were correlated with the contrast-enhanced images. Twenty-five patients were positive for pulmonary thromboembolism in the pulmonary CTAs. Of these 25 patients, nine were positive for the hyperdense lumen sign in the non-contrast CT images. The hyperdense lumen sign has an over-all sensitivity of 36.0%, specificity of 99.0%, PPV of 90.0%, and NPV of 85.6% (κ=0.449; P-value<0.001). In detecting central thromboembolism, the s...Continue Reading

References

Oct 1, 1984·AJR. American Journal of Roentgenology·S J SwensenD H Stephens
Jun 4, 1998·Radiology·E E CocheJ R Mayo
Nov 13, 1999·Chest·D D MakiA Alavi
Jan 11, 2000·AJR. American Journal of Roentgenology·D F YankelevitzC I Henschke
Jun 18, 2002·The European Respiratory Journal. Supplement·N L Müller
May 23, 2003·AJR. American Journal of Roentgenology·Jeffrey P KanneEric J Stern
Aug 14, 2003·Respiration; International Review of Thoracic Diseases·Kavita Garg, Loren Macey
Jan 23, 2004·AJR. American Journal of Roentgenology·Rocco CobelliGiovanni De Luca
Jan 25, 2005·Journal of Computer Assisted Tomography·Rocco CobelliCarla Marcato
Apr 19, 2005·Radiology·Conrad WittramJo-Anne O Shepard
Jun 24, 2005·AJR. American Journal of Roentgenology·Smita Patel, Ella A Kazerooni
Jun 2, 2006·The New England Journal of Medicine·Paul D SteinUNKNOWN PIOPED II Investigators

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Citations

Jan 7, 2014·The International Journal of Cardiovascular Imaging·Simon SunBenoît Mesurolle
Oct 24, 2013·AJR. American Journal of Roentgenology·Carol C WuJo-Anne O Shepard
Apr 17, 2015·Abdominal Imaging·Charles H MitchellPamela T Johnson
Jul 16, 2015·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Masanori IshidaKuni Ohtomo
Jan 21, 2012·Journal of Computer Assisted Tomography·Mark GoldsteinKartik Jhaveri
Jan 17, 2020·The British Journal of Radiology·Pedro Paulo Teixeira E Silva TorresEdson Marchiori
Aug 16, 2019·BMC Medical Imaging·Chiao-Hsuan ChienChee-Wai Mak
Jul 28, 2020·Internal Medicine·Yuzo FujinoHirokazu Oyamada
Aug 23, 2017·AJR. American Journal of Roentgenology·Pedro Paulo Teixeira E Silva TorresEdson Marchiori
Nov 2, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jordan A LangMalak Itani

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