PMID: 9524451Apr 1, 1997Paper

The validity of models

Advances in Dental Research
J W Wimpenny

Abstract

The ubiquity of biofilm and its classification as a microbial aggregate is discussed. Investigations into any microbial ecological problem operate at four levels: (i) in situ investigations, (ii) the use of microcosms, (iii) experimental model systems, and (iv) mathematical models. Each of these is defined and their use in biofilm research illustrated. It is concluded that all these approaches are valid and that scientific research in general and biofilm research in particular must profit by the use widely different methods if a complete understanding of a system is to be achieved.

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Citations

Jun 9, 2005·Current Microbiology·David ElliottMichael Wilson
Mar 22, 2008·Clinical Oral Investigations·Nicole Birgit ArweilerThorsten Mathias Auschill
Sep 21, 2005·Journal of Periodontology·M Robert WirthlinCharles I Hoover
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Oct 2, 2015·Dental Materials : Official Publication of the Academy of Dental Materials·Asbjørn Jokstad
May 2, 2016·Journal of Dentistry·Christina P C SimEric C Reynolds
Apr 1, 1997·Advances in Dental Research·C H Sissons
Nov 14, 2001·Pesquisa odontológica brasileira = Brazilian oral research·H E VelanoH Panzeri
Mar 23, 2018·Dentistry Journal·Ollie Yiru YuChun-Hung Chu
Mar 22, 2020·Clinical Oral Investigations·Torsten WassmannRalf Bürgers
Feb 22, 2007·Oral Microbiology and Immunology·S K FilocheC H Sissons
Dec 23, 2020·Biofouling·Débora de Souza Collares Maia Castelo-BrancoJosé Júlio Costa Sidrim
Nov 17, 2020·Frontiers in Bioengineering and Biotechnology·Martina OrianoPaola Petrini

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