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The value of a histamine H2-receptor antagonist in the management of patients with the Zollinger-Ellison syndrome

The New England Journal of Medicine

Jan 15, 1976

Charles T Richardson, Jennifer H Walsh

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Abstract

Inhibition of acid secretion by an H2-receptor antagonist (metiamide) was assessed in three patients with the Zollinger-Ellison syndrome. Metiamide (200 or 300 mg) inhibited acid secretion transiently (2 1/2 hours) by 85 to 100 per cent in all patients. Although anticholinergic drugs al...read more

Mentioned in this Paper

Anticholinergic [EPC]
Histamine Measurement
Polychemotherapy
Glycopyrrolate
Drug Evaluation
Acid Secretion
Receptors, Drug
Metabolic Inhibition
Anticholinergic Agents
Diarrhea
Paper Details
References
    • References6
    • Citations19
    • References6
    • Citations19
  • The value of a histamine H2-receptor antagonist in the management of patients with the Zollinger-Ellison syndrome

    The New England Journal of Medicine

    Jan 15, 1976

    Charles T Richardson, Jennifer H Walsh

    PMID: 616

    DOI: 10.1056/nejm197601152940304

    Abstract

    Inhibition of acid secretion by an H2-receptor antagonist (metiamide) was assessed in three patients with the Zollinger-Ellison syndrome. Metiamide (200 or 300 mg) inhibited acid secretion transiently (2 1/2 hours) by 85 to 100 per cent in all patients. Although anticholinergic drugs al...read more

    Mentioned in this Paper

    Anticholinergic [EPC]
    Histamine Measurement
    Polychemotherapy
    Glycopyrrolate
    Drug Evaluation

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    Paper Details
    References
    • References6
    • Citations19
    • References6
    • Citations19
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