The value of amniotic fluid analysis in patients with suspected clinical chorioamnionitis.

Journal of Perinatal Medicine
Elif E Gultekin-ElbirMehmet R Genç

Abstract

Objective To assess the value of incorporating amniotic fluid (AF) analysis in the management of patients with clinical chorioamnionitis. Methods This was a retrospective cohort study of all women carrying a singleton fetus and managed at our center between 2000 and 2009. We included only those women suspected of chorioamnionitis based on one or more of the following: (1) uterine tenderness, (2) maternal fever, (3) maternal and/or fetal tachycardia and (4) purulent discharge. The management was deemed to be justified if (1) pregnancy was terminated <24 weeks and histology confirmed chorioamnionitis; (2) delivery was performed expeditiously after initial assessment and histology confirmed chorioamnionitis; (3) delivery was delayed for 2-7 days and the patient completed a course of antenatal steroids before 34 weeks; and (4) delivery was delayed ≥7 days and histology was not indicative of chorioamnionitis, or delivery occurred after 37 weeks. Univariate and logistic regression analyses were used as appropriate. Results Of the 77 women with suspected chorioamnionitis, AF analysis was performed in 43 (55.8%) cases, and the management was justified in 63 (81.8%) cases based on the aforementioned criteria. Stepwise regression analysi...Continue Reading

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Citations

May 22, 2019·Journal of Perinatal Medicine·Daniel Skupski
Sep 9, 2019·Journal of Perinatal Medicine·Nardhy Gomez-LopezChaur-Dong Hsu
Feb 23, 2020·Journal of Perinatal Medicine·Jose GalazNardhy Gomez-Lopez
Dec 15, 2020·The Journal of Obstetrics and Gynaecology Research·Yuko OshimaMasatoshi Yokoyama

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