PMID: 3311134Aug 1, 1987

The value of artificial insemination with husband's semen in infertility due to failure of postcoital sperm-mucus penetration--controlled trial of treatment

British Journal of Obstetrics and Gynaecology
C M GlazenerM G Hull

Abstract

Artificial insemination with husband's semen into the cervical canal and uterine cavity (high AIH) was assessed by a randomized controlled prospective study in 46 couples whose infertility was due to failure of sperm mucus penetration, as defined by negative postcoital tests, after excluding all interfering female factors and men with sperm density less than 1 x 10(6)/ml. Seminal analysis was abnormal in 18 of the 46 men and sperm antibodies in semen were detected in 19 of the remaining 28 with normal seminal analysis. Overall, the cumulative conception rate after 6 months with AIH was 4.7 (SE 3.8)% and without treatment was 6.6 (SE 3.9)%. The results were unaffected by the findings on seminal analysis or by the presence or absence of sperm antibodies in semen. AIH appeared to be of no benefit.

References

Aug 1, 1979·Fertility and Sterility·R D NachtigallR H Glass
Mar 1, 1979·Fertility and Sterility·R H Glass, R J Ericsson
Oct 1, 1986·British Journal of Obstetrics and Gynaecology·W H James
Mar 1, 1986·British Journal of Obstetrics and Gynaecology·G L Foss, M G Hull
Aug 1, 1984·Journal of Clinical Pathology·S A Cederholm-WilliamsA C Turnbull
Apr 1, 1984·British Journal of Obstetrics and Gynaecology·R SchatsO Djahanbakhch
Apr 1, 1982·British Journal of Obstetrics and Gynaecology·M G HullD R Bromham
Nov 1, 1982·Fertility and Sterility·J F Shulman, S Shulman

Citations

Feb 1, 1996·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S G OeiM J Keirse
Apr 1, 1996·European Journal of Obstetrics, Gynecology, and Reproductive Biology·O GrigoriouA Gargaropoulos
Nov 1, 2013·Human Reproduction Update·N M van den BoogaardPatrick M M Bossuyt
May 25, 2006·Obstetrical & Gynecological Survey·F M HelmerhorstD A Grimes
Apr 1, 1996·American Journal of Reproductive Immunology : AJRI·W H KuttehB R Carr
Aug 26, 1998·BMJ : British Medical Journal·S G OeiM J Keirse
Jul 21, 2007·Reproduction : the Official Journal of the Society for the Study of Fertility·Sheena E M Lewis
May 2, 2001·Human Reproduction·S G OeiM J Keirse
Aug 31, 2004·Gynecologic and Obstetric Investigation·B J Cohlen
Oct 20, 2005·The Cochrane Database of Systematic Reviews·F M HelmerhorstD A Grimes
Nov 1, 1993·British Journal of Obstetrics and Gynaecology·P VandekerckhoveT W Harada
Feb 24, 2006·Current Opinion in Obstetrics & Gynecology·Chyong-Huey Lai, Huei-Jean Huang
Oct 10, 2009·Pharmacological Reports : PR·Marek DroździkMateusz Kurzawski
Mar 23, 2018·Obstetrics & Gynecology Science·Amena KhatunMyung-Geol Pang
Jun 1, 1990·Asia-Oceania Journal of Obstetrics and Gynaecology·M J TuckerC K Leung
Nov 22, 2017·Reproduction : the Official Journal of the Society for the Study of Fertility·G D PalermoZ Rosenwaks

Related Concepts

Palm-Leaf Reaction
Clinical Trials
Subfertility, Male
Artificial Insemination
Insemination, Artificial, Homologous
Randomization
Sperm Transport
Y-Chromosome-Bearing Sperm

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