PMID: 11314936Apr 21, 2001Paper

The value of Cloquet's node in predicting melanoma nodal metastases in the pelvic lymph node basin

Annals of Surgical Oncology
L J StrobbeB B Kroon

Abstract

A selection of melanoma patients with groin metastases can benefit from a pelvic (iliac/obturator) lymph node dissection in addition to the infrainguinal dissection. However, there are no reliable criteria to determine which patients may benefit from such an inguinal-pelvic lymphadenectomy. In 142 patients (group A) out of a review of 214 groin dissections performed between 1980 and 1994, the tumor status of Cloquet's node was traced retrospectively. In 52 additional patients (group B), the status of Cloquet's node was registered prospectively. The number of positive lymph nodes and the total numbers of retrieved nodes were recorded as well. All patients underwent a combined therapeutic inguinal-pelvic lymph node dissection between January 1995 and June 1999 in a tertiary referral center. Cloquet's node was free of disease in 18 of 39 patients with involved pelvic nodes in the retrospective study (sensitivity, 54%; negative predictive value, 83%). In the prospective study, 9 of the 20 patients with involved pelvic nodes had a tumor-free Cloquet's node (sensitivity, 55%; negative predictive value, 78%). Additional immunohistochemical staining of Cloquet's node resulted in a sensitivity of 65%. In the combined group A&B, the numb...Continue Reading

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May 26, 1999·Annals of Surgical Oncology·L J StrobbeB B Kroon
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Citations

Jan 3, 2003·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·L KretschmerW Becker
Sep 16, 2014·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·C A WestH Peach
Mar 25, 2015·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·N MozzilloC Caracò
Jan 21, 2010·Melanoma Research·Javier SoteldoAlessandro Testori
Nov 28, 2018·Journal of Surgical Oncology·Edmund K Bartlett

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