PMID: 8042877Jan 1, 1994Paper

The value of Doppler ultrasound in the diagnosis and management of twin-to-twin transfusion syndrome

Archives of Gynecology and Obstetrics
Y OhnoY Tomoda


To evaluate the efficiency of the Doppler examination of umbilical arterial blood flow for the antenatal diagnosis and the monitoring of fetal condition during intrauterine treatment of twin-to-twin transfusion syndrome (TTTS), we studied 33 pairs of twins including 5 TTTS cases. In all cases umbilical arterial blood flow was examined by Doppler ultrasound and pulsatility index (PI) was calculated as umbilical arterial impedance. In twins with TTTS, PI of the recipient was outside the normal range and the difference of PI was greater than +0.5. In discordant twins without TTTS and concordant twins, the PI was within the normal range and the difference of PI ranged from -0.5 to +0.5. In 2 cases these findings were found before the appearance of fetal hydrops. In 2 TTTS cases transmaternal digitalization prevented the development of hydrops in the recipient. The difference of PI decreased with improvement in the fetal condition, and vice versa. Our data suggested that, in cases with TTTS, Doppler examination of umbilical arterial blood flow was effective in predicting fetal hydrops. Doppler was also very useful for monitoring the fetal condition during intrauterine treatment.


Jun 1, 1985·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·J De LiaT A Jennison
Dec 1, 1985·American Journal of Obstetrics and Gynecology·G FarmakidesB Rochelson
Sep 1, 1986·British Journal of Obstetrics and Gynaecology·R L ErskineG A Murnaghan
Nov 1, 1986·American Journal of Obstetrics and Gynecology·B K WittmannL D Wadsworth
May 1, 1982·Radiology·J N BrennanE M Bellon
Mar 1, 1965·The Journal of Pediatrics·A R RAUSENL STRAUSS

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Dec 29, 1998·Current Opinion in Obstetrics & Gynecology·K A Filkins, S E Beverly
Feb 4, 1999·Baillière's Clinical Obstetrics and Gynaecology·W B Giles
Aug 26, 1998·Obstetrics and Gynecology Clinics of North America·N W Hendrix, S P Chauhan
May 21, 2016·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Eftichia KontopoulosRuben A Quintero
Apr 23, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·Andres F EspinozaJimmy Espinoza

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