PMID: 15387977Sep 25, 2004Paper

The value of Helicobacter pylori stool antigen ImmunoCard STAT in diagnosis of HP infection and assessing of eradication of HP

Zhonghua yi xue za zhi
Hong Cheng, Fu-lian Hu

Abstract

To evaluate the value of Helicobacter pylori (Hp) stool antigen ImmunoCard STAT (HpSA ImmunoCard STAT) in diagnosis of Hp infection and assessment of eradication of Hp. Stool specimens were collected from 80 patients with upper gastrointestinal symptoms, 41 males and 39 females, aged 18 - 73, 40 of which undergoing gastroscopy and having never received Hp eradicating regimen (group A) and another 40 of which undergoing follow-up examination (group B). HpSA ImmunoCard STAT was used to detect the Hp status in the specimens of stool. Rapid urease test, Hp culture, and Warthin-Starry silver staining were used as "gold standards" to evaluate the Hp status of the biopsy specimens. (13)C-urea breath test ((13)C-UBT) was used as the "gold standard" for the patients that did not undergo gastroscopy. Part of the biopsy specimens of gastric mucosa underwent HpSA test too. The result was considered positive when 2 of the 3 tests in the "gold standard" were positive or culture of Hp was positive. The sensitivity, specificity, and accuracy of HpSA test for the 80 patients as a whole were 100%, 93.2%, and 96.3%, not significantly different from those of the "gold standard". The sensitivity, specificity, and accuracy of HpSA test for the 40 pa...Continue Reading

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