The value of MRI in early Perthes' disease: an MRI study with a 2-year follow-up

Pediatric Radiology
T Lahdes-VasamaE Marttinen

Abstract

Eleven hips in nine patients with Perthes' disease were studied by plain radiography at 3-month and MRI at 6-month intervals over a period of 2 years. The aim was to clarify the value of MRI in estimating epiphyseal involvement and in predicting uncoverage of the epiphysis. Signal intensities of the epiphysis and metaphysis were visually evaluated from T1- (T1W) and T2-weighted (T2W) images. The extent of decreased signal intensity (DSI) in the epiphyses was volumetrically calculated from T1W images and then compared with follow-up radiographs. The area of epiphyseal DSI corresponding best with Catterall's classification was seen by MRI 3-8 months after the first symptoms. MRI images obtained earlier usually showed less involvement than the follow-up radiographs. However, two features predicting extensive epiphyseal necrosis were: (1) DSI on both T1W and T2W images covering over two-thirds of the epiphysis and (2) diffuse bone marrow oedema of the femoral neck and metaphysis. When T1W images showed a reappearance of high signal intensity patches in the lateral quarter of the epiphysis, no clinically significant uncoverage was seen during the follow-up. Extensive epiphyseal necrosis can, therefore, sometimes be predicted by MRI ...Continue Reading

Citations

Mar 20, 1999·Current Opinion in Pediatrics·E J Wall
Nov 11, 2005·Journal of Pediatric Orthopedics. Part B·Edward GentNicholas M P Clarke
Apr 9, 2008·Journal of Pediatric Orthopedics. Part B·Uwe MausFritz U Niethard
Apr 15, 2014·Orthopaedics & Traumatology, Surgery & Research : OTSR·C BauninJ Sales de Gauzy
Aug 7, 2012·Journal of the American College of Radiology : JACR·Sarah S MillaSandra L Wootton-Gorges
Jun 23, 2015·Best Practice & Research. Clinical Rheumatology·E S SenA V Ramanan
Dec 5, 2012·Diagnostic and Interventional Imaging·J-R BoutaultN Sans
Sep 18, 2009·Acta Orthopaedica. Supplementum·Ola Wiig
Jul 18, 2014·The Journal of Bone and Joint Surgery. American Volume·Harry K W KimJ Anthony Herring

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