The value of MRI in the diagnosis of primary biliary cirrhosis and assessment of liver fibrosis

PloS One
Ying MengMingming Liu

Abstract

To evaluate MRI findings in patients with primary biliary cirrhosis (PBC) and to determine the value of MRI in the diagnosis of PBC and assessment of liver fibrosis. This study reviewed the prevalence of MRI abnormalities seen in 45 PBC patients in the past four years, including 33 patients who underwent liver biopsy. Correlation between the MRI findings and the pathological stage was determined. There were 33 patients who underwent liver biopsy. Twenty-five patients (75.8%) had non-homogeneous changes in the liver signal intensity, 25 (75.8%) had a periportal halo sign, and 29 (87.9%) had lymphadenopathy. The short axis of the enlarged lymph nodes was a mean of 1.2±0.3 cm. A strong positive correlation was observed between histological stage and the inhomogeneity of liver signal intensity (P<0.001). There were significant differences among the four histological stages based on the periportal halo sign (P=0.034), and the grading of the periportal halo sign was found to be significantly correlated with the histological stage (P<0.001). Grading of the periportal halo sign was significantly different at stage II versus III, and stage III versus IV; no significant difference was found between stages I and II. There were also no sig...Continue Reading

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Citations

Nov 26, 2015·Clinics in Liver Disease·Christophe Corpechot
Sep 19, 2016·Abdominal Radiology·Melinda J YehBenjamin M Yeh
Dec 28, 2016·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Jing-Jing YangJun Li
Apr 27, 2020·European Radiology·Ilkay S IdilmanSudhakar K Venkatesh
Dec 14, 2016·World Journal of Hepatology·Ying-Qiu Huang
Jul 9, 2021·The British Journal of Radiology·Sarah Pötter-LangMichael Trauner

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Methods Mentioned

BETA
biopsy
biopsies

Software Mentioned

SPSS

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