PMID: 2496671Apr 1, 1989Paper

The value of protective isolation procedures in cardiac allograft recipients

The Annals of Thoracic Surgery
T R WalshB P Griffith

Abstract

The impact of protective isolation on the incidence of infection in 60 cardiac transplant recipients (mean age, 49.2 years) was studied in a prospective randomized trial. Thirty patients were randomized to protective isolation, which consisted of private room, hat, mask, sterile gown, and handwashing. Thirty patients were randomized to no isolation, which meant they recovered in a crowded, open intensive care unit and were adjacent to recipients of liver transplants or patients who were on the trauma, neurosurgical, and general surgical services, many of whom had an infection of the incision or a pulmonary infection. There was no difference between groups in the proportion of patients in whom infection developed (chi 2[1] = 0.27; p = 0.6), the number of infection-related deaths (2 in each group), the types of infection (bacterial, viral, fungal, or protozoal), or the overall outcome. Because protective isolation offered no benefit over standard care in protecting these patients from infections or the associated complications, we have discontinued its routine use after cardiac transplantation.

References

Jan 15, 1987·The New England Journal of Medicine·B P GriffithH T Bahnson
Jan 1, 1971·Annals of Internal Medicine·E B StinsonJ S Remington

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Citations

Apr 16, 2009·Current Infectious Disease Reports·Anton Y PelegFernanda P Silveira
Sep 15, 2005·The Journal of Cardiovascular Nursing·Frances M Hoffman
Jul 1, 1992·Mayo Clinic Proceedings·M R KeatingR C Walker
Aug 10, 1999·The Journal of Hospital Infection·O M Murphy, F K Gould
Sep 1, 1994·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·O C TablanM M McNeil
Mar 16, 2012·The Cochrane Database of Systematic Reviews·Amy DrahotaTaraneh P Dean
Feb 21, 2004·Critical Care Nursing Quarterly·Carol R WadeSharon M Augustine
Aug 6, 1994·Journal of Intensive Care Medicine·L OhlerP DiSanto

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