The value of serum creatine kinase in predicting the risk of rhabdomyolysis-induced acute kidney injury: a systematic review and meta-analysis

Clinical and Experimental Nephrology
Saeed SafariIraj Najafi

Abstract

Identifying the potential effective factors of rhabdomyolysis-induced acute kidney injury (AKI) is of major importance for both treatment and logistic concerns. The present study aimed to evaluate the value of creatine kinase (CK) in predicting the risk of rhabdomyolysis-induced AKI through meta-analysis. Two reviewers searched the electronic databases of Medline, EMBASE, Cochrane library, Scopus, and Google Scholar. Data regarding study design, patient characteristics, number of cases, mean and screening characteristics of CK, and final patient outcome were extracted from relevant studies. Pooled measures of standardized mean difference, OR, and diagnostic accuracy were calculated using STATA version 11.0. 5997 non-redundant studies were found (143 potentially relevant). 27 articles met the inclusion criteria but 9 were excluded due to lack of data. The correlation between serum CK and AKI occurrence was stronger in traumatic cases (SMD = 1.34, 95 % CI = 1.25-1.42, I (2) = 94 %; p < 0.001). This correlation was more prominent in crush-induced AKI (adjusted OR = 14.7, 95 % CI = 7.63-28.52, I (2) = 0.0 %; p = 0.001). Area under the ROC curve of CK in predicting AKI occurrence was 0.75 (95 % CI = 0.71-0.79). The results of this m...Continue Reading

References

Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
May 2, 2000·AJR. American Journal of Roentgenology·C L Sistrom, P J Mergo
Sep 5, 2001·Kidney International·M S SeverUNKNOWN Marmara Earthquake Study Group
Jan 17, 2002·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·T Watanabe
Jun 24, 2004·The Journal of Trauma·Carlos V R BrownGeorge C Velmahos
Oct 7, 2004·The American Journal of Medicine·Derek M FineJoseph A Eustace
Jan 27, 2005·The American Journal of Emergency Medicine·William G FernandezWilliam K Chiang
Apr 21, 2005·BMC Medical Research Methodology·Stela Pudar HozoIztok Hozo
Nov 3, 2006·Pediatrics·Rebekah MannixMarc Baskin
Apr 17, 2009·The Cochrane Database of Systematic Reviews·Jill FerrariTrevor D Prior
Jun 12, 2010·Journal of Critical Care·Shunji KasaokaTsuyoshi Maekawa
Jul 22, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Mehmet S SeverRaymond Vanholder
Sep 10, 2010·The American Journal of Emergency Medicine·Najafi IrajBoroumand Behrooz
Nov 16, 2011·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Mostafa Alavi-MoghaddamMostafa Hosseini
Sep 8, 2012·Journal of Burn Care & Research : Official Publication of the American Burn Association·Ian J StewartKevin K Chung
Jan 11, 2013·Kidney International·Philip Kam Tao LiUNKNOWN World Kidney Day Steering Committee 2013
May 25, 2013·The American Journal of Emergency Medicine·Chun-Yu ChenHan-Ping Wu
Sep 4, 2013·JAMA Internal Medicine·Gearoid M McMahonSushrut S Waikar
Dec 25, 2013·PloS One·Eva RodríguezJulio Pascual

❮ Previous
Next ❯

Citations

Jun 3, 2016·Journal of Minimal Access Surgery·Gulsah KaraorenEyup Gumus
Dec 19, 2016·Clinical Chemistry and Laboratory Medicine : CCLM·Shufa ZhengYu Chen
Apr 25, 2018·Hospital Practice·Numan AlabdanAbdulla A Al-Sayyari
Sep 2, 2018·BMJ Case Reports·Fabian EchterdiekJörg Latus
Jan 16, 2019·Acta Anaesthesiologica Scandinavica·Jens MichelsenJørgen Wiis
Jan 12, 2020·The Journal of Pharmacology and Experimental Therapeutics·Kazuaki TaguchiToru Maruyama
Oct 27, 2017·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Marie VangstadDag Jacobsen
May 23, 2019·Archives of Pathology & Laboratory Medicine·Ron B Schifman, Daniel R Luevano
Jun 25, 2016·Clinical Chemistry and Laboratory Medicine : CCLM·Giuseppe Lippi, Mario Plebani
Jun 2, 2018·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Jochen GilleManuel F Struck
Jan 27, 2019·Irish Journal of Medical Science·Mary Clare McKennaPeter Lavin
Mar 25, 2020·Emergency Nurse : the Journal of the RCN Accident and Emergency Nursing Association·Clare O'Carroll, Rob Fenwick
May 1, 2020·World Journal of Emergency Medicine·Peng-Chao GuoHui-Ming Zhong
Jan 6, 2021·Journal of Nephrology·Maxime Desgrouas, Thierry Boulain
Nov 25, 2020·Journal of Occupational and Environmental Medicine·Caíque Olegário DinizFabiano Trigueiro Amorim
Jan 30, 2021·Critical Care : the Official Journal of the Critical Care Forum·Christina ScharfInes Schroeder
Jan 12, 2019·The American Journal of Emergency Medicine·Brit LongMichael Gottlieb
Apr 28, 2021·Wiener klinische Wochenschrift·Antonia-Therese KietaiblPeter Fasching
Jun 3, 2021·Journal of Clinical Medicine·Chien-Wen YangYichen Wang
Jun 2, 2021·Anaesthesia Critical Care & Pain Medicine·Julien PottecherHervé Quintard
Sep 25, 2021·Annals of Intensive Care·Virginie TarazonaAnatole Harrois

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.