The value of the radio-isotope hepatogram in the jaundiced patient.

The British Journal of Surgery
A WatsonB Torrance

Abstract

The distinction between 'medical' and 'surgical' jaundice is often difficult due to the lack of specificity of biochemical liver function tests, and the difficulty in assessing hepatocellular function and biliary tract patency in the jaundiced patient. We present a noninvasive isotopic technique which gives reliable information on these parameters, resulting in a high degree of accuracy in the classification of jaundice. 131I Rose Bengal, which is handled by the liver like bromsulphthalein, is administered intravenously and count rates during hepatic uptake and biliary excretion are recorded over the liver, biliary tract and duodenum using a gamma camera/computer system, into which is built an electronic light pen, so that particular areas of interest can be studied. Blood clearance of the iostope is simultaneously measured, and from these data the T 1/2 of uptake, the plasma retention and the excretion quotient are determined. The results of the first 80 examinations show that by qualitative assessment of the uptake and excretory phases of the 'hepatogram' and by determination of the T 1/2 and excretion quotient, jaundice has been classified with an 86 per cent accuracy in cases where the diagnosis is not apparent from clinica...Continue Reading

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Citations

Apr 1, 1980·European Journal of Nuclear Medicine·M TaavitsainenE Tähti
Aug 1, 1980·European Journal of Nuclear Medicine·R W NicholsonH J Testa
Dec 31, 2010·Indian Journal of Anaesthesia·Indu A Chadha
Jan 1, 1979·Scandinavian Journal of Gastroenterology·M TaavitsainenK Tallroth

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