The value of tumor markers in a mixed tumor, mucinous and neuroendocrine carcinoma of the ovary.

Gynecologic Oncology
H Y NganH K Ma

Abstract

Serum CA125 is frequently used to monitor the treatment response and to detect early recurrence during the follow-up of patients who have epithelial ovarian tumors. In this report, the level of serum CA125 and urinary 5-hydroxyindole acetic acid of a patient with a carcinoid tumor which occurred in association with a mucinous adenocarcinoma of the ovary is described. The level of serum CA125 decreased despite the presence of a clinically progressive tumor. There was a rise of the 5-hydroxyindole acetic acid level 16 weeks before pelvic recurrence was detected clinically. This indicates that it was the neuroendocrine component, and not the mucinous component of the tumor, that was not responsive to the chemotherapy. The problem of using tumor markers to monitor patients with mixed tumors is discussed.

References

Sep 1, 1987·Gynecologic Oncology·F ZanaboniG Bolis
Jul 1, 1984·American Journal of Obstetrics and Gynecology·R C BastR C Knapp

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Citations

Sep 1, 1993·Seminars in Surgical Oncology·I E Wanke
Apr 27, 2007·The American Journal of Surgical Pathology·Emanuela VerasAnais Malpica
Sep 22, 2007·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Marie GrandjeanEtienne Marbaix
Oct 16, 2014·World Journal of Surgical Oncology·Eun Young KiSoo Young Hur
Dec 5, 2019·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Ying ZhuWei Zheng
Jun 1, 2006·Annales de pathologie·Valérie Hervieu, Jean-Yves Scoazec

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