PMID: 6975645Dec 14, 1981Paper

The variable gain element of the vestibulo-ocular reflex is common to the optokinetic system of the cat

Brain Research
J L Demer

Abstract

The gain (slow-phase eye velocity/head velocity) of the vestibulo-ocular reflex (VOR) of 6 alert cats was sequentially adapted to values between 0.2 and 1.66 by the chronic wearing of visual reversing or 2 X magnifying spectacles, combined with forced rotation in the light. Gain was measured during sinusoidal oscillation in darkness at 0.05 Hz at a peak velocity of about 30 degrees/s. In each state of VOR gain adaptation, optokinetic nystagmus (OKN) and optokinetic afternystagmus (OKAN) were measured in a full-field optokinetic drum at velocities of 20-80 degrees/s. Steady-state, slow-phase, optokinetic eye velocity nearly equaled low drum velocities, but saturated at higher velocities and declined when drum velocity further increased. The saturation velocity varied in relation to VOR gain, ranging from 10-20 degrees/s at a VOR gain of 0.2-0.4, to 65 degrees/s at a VOR gain of 1.66. The means that the variable gain element of the VOR is shared by the optokinetic system (OKS). OKAN, measured in darkness, had a roughly exponential decay. The time constant of OKAN (Tokan) also varied with VOR gain, ranging form about 2 s at a VOR gain of 0.2, to 10 s at a VOR gain of 1.66. This is a novel finding which suggests that the velocity-s...Continue Reading

References

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Citations

Jan 1, 1986·Biological cybernetics·D A RobinsonS E Gordon
Jan 1, 1984·Journal of Psychiatric Research·S Levin
Jan 1, 1990·Vision Research·W FreedmanJ G McElligott
Apr 1, 1984·Brain Research·N P StrongR C Van Sluyters
Sep 1, 1984·Behavioural Brain Research·L HainlineJ Turkel
Jun 19, 1996·Annals of the New York Academy of Sciences·B W PetersonN T Slater
Dec 6, 2002·Journal of Neurophysiology·Y HirataS M Highstein
Mar 1, 1997·Journal of Neurophysiology·E Marsh, R Baker

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