The variable genomic architecture of isolation between hybridizing species of house mice

Evolution; International Journal of Organic Evolution
Katherine C TeeterP K Tucker

Abstract

Studies of the genetics of hybrid zones can provide insight into the genomic architecture of species boundaries. By examining patterns of introgression of multiple loci across a hybrid zone, it may be possible to identify regions of the genome that have experienced selection. Here, we present a comparison of introgression in two replicate transects through the house mouse hybrid zone through central Europe, using data from 41 single nucleotide markers. Using both genomic and geographic clines, we found many differences in patterns of introgression between the two transects, as well as some similarities. We found that many loci may have experienced the effects of selection at linked sites, including selection against hybrid genotypes, as well as positive selection in the form of genotypes introgressed into a foreign genetic background. We also found many positive associations of conspecific alleles among unlinked markers, which could be caused by epistatic interactions. Different patterns of introgression in the two transects highlight the challenge of using hybrid zones to identify genes underlying isolation and raise the possibility that the genetic basis of isolation between these species may be dependent on the local populat...Continue Reading

References

Dec 1, 1988·Genetical Research·F VanlerbergheF Bonhomme
Dec 1, 1986·Heredity·N Barton, B O Bengtsson
Aug 1, 1973·Heredity·W G Hunt, R K Selander
Apr 1, 1997·Mammalian Genome : Official Journal of the International Mammalian Genome Society·E M PragerRichard D Sage
Aug 11, 2000·Evolution; International Journal of Organic Evolution·L H Rieseberg
Feb 13, 2001·International Journal for Parasitology·Jean-Marc DerotheCatherine Moulia
May 1, 2001·Evolution; International Journal of Organic Evolution·H M TalleyR C Karn
Jun 8, 2001·Evolution; International Journal of Organic Evolution·C Alex Buerkle, L H Rieseberg
Nov 6, 1986·Nature·Richard D SageA C Wilson
Jun 9, 2004·Proceedings of the National Academy of Sciences of the United States of America·Laura K Reed, Therese A Markow
Sep 16, 2004·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Radka StorchováJiri Forejt
Nov 4, 2004·Evolution; International Journal of Organic Evolution·Bret A PayseurMichael W Nachman
Feb 16, 2007·Evolution; International Journal of Organic Evolution·Andrea L SweigartJohn H Willis
Apr 19, 2007·Evolution; International Journal of Organic Evolution·Miloš MacholánJaroslav Piálek
Nov 21, 2007·Genome Research·Katherine C TeeterP K Tucker
Oct 11, 2008·Trends in Ecology & Evolution·C Alex Buerkle, Christian Lexer
Feb 27, 2009·Molecular Ecology·Zachariah Gompert, C Alex Buerkle
Mar 1, 2010·Molecular Ecology Resources·Zachariah Gompert, C Alex Buerkle
Aug 1, 1992·Evolution; International Journal of Organic Evolution·P K TuckerEva M Eicher
Dec 1, 1997·Evolution; International Journal of Organic Evolution·Christina M LaukaitisRobert C Karn

Citations

Oct 12, 2012·Proceedings. Biological Sciences·Jana AlbrechtováJaroslav Piálek
Dec 28, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Zachariah GompertC Alex Buerkle
Dec 28, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Michael W Nachman, Bret A Payseur
Mar 4, 2014·PLoS Genetics·Leslie M TurnerBret A Payseur
May 5, 2012·Genetics·Michael A WhiteBret A Payseur
May 19, 2012·Genetics·Polly CampbellMichael W Nachman
Feb 19, 2014·Nature Reviews. Genetics·Ole SeehausenAlex Widmer
Nov 20, 2013·Proceedings of the National Academy of Sciences of the United States of America·Yoosook LeeGregory C Lanzaro
Aug 26, 2014·The Journal of Heredity·Richard G Harrison, Erica L Larson
Aug 21, 2014·Evolution; International Journal of Organic Evolution·Scott A TaylorIrby Lovette
Dec 14, 2011·Trends in Ecology & Evolution·Asher D Cutter
Dec 5, 2012·Evolution; International Journal of Organic Evolution·Richard G Harrison
Mar 8, 2011·Molecular Ecology·C Alex BuerkleT L Parchman
Jan 18, 2013·Journal of Evolutionary Biology·R AbbottD Zinner
Sep 13, 2012·Molecular Ecology·Jill A HamiltonSally N Aitken
Apr 24, 2013·Ecology and Evolution·Erica L LarsonRichard G Harrison
Sep 6, 2012·Evolution; International Journal of Organic Evolution·Stuart J E BairdJoëlle Goüy de Bellocq
Mar 7, 2013·Evolution; International Journal of Organic Evolution·Victoria L Pritchard, Suzanne Edmands
Sep 17, 2013·Evolution; International Journal of Organic Evolution·Zachariah GompertC Alex Buerkle
Jul 7, 2011·Evolution; International Journal of Organic Evolution·Shannon R McDermott, Mohamed A F Noor
Oct 31, 2012·Evolution; International Journal of Organic Evolution·Maria Dzur-GejdosovaJiri Forejt
Apr 28, 2011·Evolution; International Journal of Organic Evolution·Miloš MacholánJaroslav Piálek
Mar 28, 2013·Ecology and Evolution·Zachariah GompertMatthew L Forister
Oct 10, 2013·Molecular Ecology·Zachariah Gompert, C Alex Buerkle
Oct 19, 2010·Aggressive Behavior·Ludovít DurejeJaroslav Piálek
Nov 10, 2011·Molecular Ecology·Ludovic DuvauxPierre Boursot
Jul 5, 2012·Evolution; International Journal of Organic Evolution·Zachariah GompertC Alex Buerkle
Jan 27, 2012·Evolution; International Journal of Organic Evolution·Leslie M TurnerBettina Harr
Mar 27, 2012·Molecular Ecology·Zachariah Gompert

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