PMID: 7007821Jan 1, 1980Paper

The variation in frequency with which markers are transduced by phage P1 is primarily a result of discrimination during recombination

Molecular & General Genetics : MGG
B J Newman, M Masters

Abstract

The efficiency of recovery of P1 transductants is marker dependent and normally varies over a 25-fold range. UV irradiation of either transducing lysates for recipient cells results in a selective stimulation of the transduction of markers which are normally transduced poorly. As a result the range in frequency of transduction is reduced to about 3-fold and resembles the gene frequency distribution expected in the donor cells. We conclude that P1 transducing lysates are likely to contain a random sample of donor DNA but that the recombination system of the recipient cell exhibits a preference for the DNA of some regions over that of others. Damage to DNA presumably overrides this specificity.

References

Jan 1, 1978·Annual Review of Genetics·K B Low, D D Porter
Mar 1, 1976·Bacteriological Reviews·B J BachmannA L Taylor
Sep 25, 1974·Journal of Molecular Biology·R M BenbowR L Sinsheimer
Feb 14, 1968·Journal of Molecular Biology·S Cooper, C E Helmstetter
Mar 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·M Masters
Aug 4, 1971·Nature: New Biology·M Masters, P Broda

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Citations

Jan 1, 1983·Molecular & General Genetics : MGG·K K Young, G Edlin
Nov 1, 1988·Molecular & General Genetics : MGG·M C HanksM Masters
Jan 1, 1984·Molecular & General Genetics : MGG·M MastersC M Henry
Jun 27, 2002·Current Urology Reports·J D Sobel, T Lundstrom
Apr 1, 1992·Journal of Bacteriology·P D MoirM Masters
Mar 1, 1982·Journal of Bacteriology·J T BarrettB Ely

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