The varus alignment and morphologic alterations of proximal tibia affect the onset of medial knee osteoarthritis in rural Japanese women: Case control study from the longitudinal evaluation of Matsudai Knee Osteoarthritis Survey

Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association
Yukimasa HiganoNaoto Endo

Abstract

Relationship malalignment of the knee and the onset of knee OA are unclear. Moreover, it has not been clarified whether malalignment of the knee affects the morphological change of the proximal tibia. The purpose of current study was to investigate whether varus knee alignment and morphological change of the proximal medial tibia influence the onset of medial knee OA and to clarify the relationship between them. The subjects comprised 736 knees from 390 women that went under both the first survey in 1979 and the fourth survey in 2000 in the Matsudai district in Niigata Prefecture in Japan. None of the subjects demonstrated radiographic knee OA at the first survey. OA was graded according to the Kellgren-Lawrence classification and the subjects were divided according to the OA grades in the forth survey into the 3 groups (non-OA, early OA, and advanced OA). Age, BMI, Femorotibial angle (FTA), the tibial plateau angle and medial tibial cortical bone thickness (MTCBT) were measured. We performed multivariate logistic regression analysis using the stepwise method to identified the risk factors regarding onset of knee OA and calculated the odds ratio (OR) and 95% confidence intervals (95% CI). Advanced OA had a significantly higher ...Continue Reading

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Citations

Feb 1, 2017·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Tomoharu MochizukiNaoto Endo
Dec 20, 2019·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Tomoharu MochizukiYuji Tanabe
Feb 1, 2020·Journal of Bone and Mineral Metabolism·Keiichiro SomeyaNaoto Endo
Mar 30, 2019·Journal of Experimental Orthopaedics·Tomoharu MochizukiNaoto Endo
Oct 18, 2020·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Tomoharu MochizukiHiroyuki Kawashima
Jan 12, 2021·Bio-medical Materials and Engineering·Takahiro MoriYuji Tanabe

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