The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea

Marine Drugs
Samuel D RobinsonHelena Safavi-Hemami

Abstract

The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as research tools, drug leads, and drugs. In this article, we present the venom gland transcriptome of C. gloriamaris, revealing this species' conotoxin repertoire. More than 100 conotoxin sequences were identified, representing a valuable resource for future drug discovery efforts.

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Citations

Mar 10, 2018·International Journal of Molecular Sciences·S W A Himaya, Richard J Lewis
Dec 8, 2017·Toxins·Bingmiao GaoQiong Shi
Nov 2, 2018·Marine Drugs·Ying FuSulan Luo
Feb 16, 2019·Molecular & Cellular Proteomics : MCP·Carolina MöllerFrank Marí
May 20, 2018·Journal of Proteomics·Helena Safavi-HemamiBaldomero M Olivera
May 1, 2019·Molecular & Cellular Proteomics : MCP·Carolina MöllerFrank Marí
Jun 8, 2021·RSC Medicinal Chemistry·Ashlin TurnerDavid J Craik
Oct 22, 2019·Chemical Reviews·Ai-Hua JinPaul F Alewood

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Datasets Mentioned

BETA
JF510902.1
SRR5499408

Software Mentioned

house
Conoserver
fqtrim
BBnorm ecc
prinseq
BBtools
Geneious
lite
Trinity
blastx

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