The Very Low Frequency of Epstein-Barr JC and BK Viruses DNA in Colorectal Cancer Tissues in Shiraz, Southwest Iran

Polish Journal of Microbiology
Jamal SarvariSeyed Younes Hosseini

Abstract

Viruses including Epstein-Barr virus (EBV), JCV and BKV have been reported to be associated with some cancers. The association of these viruses with colorectal cancers remains controversial. Our objective was to investigate their infections association with adenocarcinoma and adenomatous polyps of the colon. Totally, 210 paraffin-embedded tissue specimens encompassing 70 colorectal adenocarcinoma, 70 colorectal adenomatous and 70 colorectal normal tissues were included. The total DNA was extracted, then qualified samples introduced to polymerase chain reaction (PCR). The EBV, JCV and BKV genome sequences were detected using specific primers by 3 different in-house PCR assays. Out of 210 subjects, 98 cases were female and the rest were male. The mean age of the participants was 52 ± 1.64 years. EBV and JCV DNA was detected just in one (1.42%) out of seventy adenocarcinoma colorectal tissues. All adenomatous polyp and normal colorectal tissues were negative for EBV and JCV DNA sequences. Moreover, all the patients and healthy subjects were negative for BKV DNA sequences. The results suggested that EBV and JCV genomes were not detectable in the colorectal tissue of patients with colorectal cancer in our population. Hence, BKV migh...Continue Reading

References

Nov 20, 1998·Pathology, Research and Practice·Y S KimD Lee
Jun 23, 1999·Proceedings of the National Academy of Sciences of the United States of America·L LaghiC R Boland
Jan 4, 2003·Gastroenterology·J Hernández LosaA Tenorio
Nov 8, 2003·World Journal of Gastroenterology : WJG·Huan-Xin LiuKai-Tai Yao
Dec 4, 2003·International Journal of Cancer. Journal International Du Cancer·Yoshihiko HoshidaKatsuyuki Aozasa
Mar 12, 2005·CA: a Cancer Journal for Clinicians·D Max ParkinPaola Pisani
May 2, 2007·International Journal of Cancer. Journal International Du Cancer·Annika LundstigJoakim Dillner
Oct 31, 2008·Journal of Digestive Diseases·Mojgan ForoutanMohammad Reza Zali
Dec 17, 2008·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S M MousaviZ Seddighi
Dec 25, 2008·Neoplasia : an International Journal for Oncology Research·Katsuhiko NoshoShuji Ogino
Jan 27, 2009·International Journal of Cancer. Journal International Du Cancer·Valentina MilitelloLuisa Barzon
Jun 10, 2009·Seminars in Cancer Biology·Johanna R AbendMichael J Imperiale
Jun 4, 2010·Journal of Clinical Gastroenterology·Dana E Rollison
Nov 3, 2010·Clinics in Colon and Rectal Surgery·Fatima A Haggar, Robin P Boushey
Nov 12, 2010·The Lancet Oncology·Danielle CollinsDesmond C Winter
Jan 6, 2011·Pathology Oncology Research : POR·Maryam KadivarNiloufar Hosseini
Feb 8, 2011·CA: a Cancer Journal for Clinicians·Ahmedin JemalDavid Forman
Jun 1, 2011·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Pawel KarpinskiMaria Malgorzata Sasiadek
May 19, 2012·PloS One·Xiaozhou MouCharlie Xiang
Mar 6, 2013·Journal of Cancer·Vlado AntonicMina Izadjoo
Oct 15, 2013·The Journal of Infection·Michelle Pinto, Simon Dobson
Jun 18, 2014·Infectious Agents and Cancer·Loretta FiorinaVittorio Perfetti
Oct 24, 2014·Cancers·Yan ChenPenelope Duerksen-Hughes
Nov 18, 2014·World Journal of Gastroenterology : WJG·Emanuele SinagraAroldo Gabriele Rizzo
May 27, 2015·Viruses·Robert Hollingworth, Roger J Grand
Jun 3, 2015·Jundishapur Journal of Microbiology·Mahsa MoeiniMohammad Amin Behzadi
Aug 8, 2015·Polish Journal of Pathology : Official Journal of the Polish Society of Pathologists·Farzaneh TafviziReza Assareh
Dec 3, 2015·Asian Pacific Journal of Cancer Prevention : APJCP·Shahab MahmoudvandJamal Sarvari
Jan 1, 2015·Polish Journal of Microbiology·Dorota Polz-GruszkaMałgorzata Polz-Dacewicz

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Citations

Nov 2, 2018·Human Vaccines & Immunotherapeutics·Shahinaz BedriSemir Vranic
Nov 27, 2019·Infectious Diseases·Rasoul ShavalehFakhradin Ahmadi Kanrash
Mar 27, 2019·BMC Research Notes·Razieh DowranJamal Sarvari
Nov 5, 2020·International Journal of Molecular Sciences·Martin MarônekCarmine Stolfi

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