The vimentin-GFA protein transition in rat neuroglia cytoskeleton occurs at the time of myelination

Journal of Neuroscience Research
D Dahl

Abstract

Extraction with Triton, a nonionic detergent, is a common procedure to prepare intermediate filament enriched fractions from cells maintained in culture. The Triton-Insoluble fraction is called a cytoskeletal preparation. Using this procedure, we previously demonstrated that vimentin and glial fibrillary acidic protein (GFA) are major cytoskeletal proteins of neuroglia, in newborn and adult rat brain, respectively. In the present communication we report that the vimentin-GFA transition in rat brain occurs during the 2nd-3rd week, ie, at the time of rapid myelination when dividing glioblasts in white matter differentiate into oligodendroglia and interfascicular astrocytes.

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Citations

Mar 14, 2002·The Journal of Comparative Neurology·Rose HanburyJeffrey H Kordower
Dec 1, 1990·Journal of Neuroscience Research·M L EstesB P Barna
Jan 1, 1986·Acta Neuropathologica·D SchifferG Giaccone
Sep 1, 1992·Neurochemical Research·W T NortonC F Brosnan
Nov 1, 1989·The Histochemical Journal·M J WarburtonP S Rudland
Oct 1, 1986·Journal of Neurocytology·A Bignami, D Dahl
Feb 1, 1988·Journal of Neurocytology·J Ciesielski-TreskaD Aunis
Mar 6, 2007·Cellular and Molecular Neurobiology·Ariane ZamonerRegina Pessoa-Pureur
Mar 1, 1984·Developmental Biology·P BovolentaC A Mason
Feb 1, 1989·Brain Research. Developmental Brain Research·K W McDermott, P L Lantos
Nov 20, 1992·Brain Research. Developmental Brain Research·C F McCabe, G J Cole
Sep 1, 1991·Brain Research. Molecular Brain Research·I CohenM Schwartz

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