The viral approach to breast cancer immunotherapy

Journal of Cellular Physiology
Atefeh ArabJavad Behravan

Abstract

Despite years of intensive research, breast cancer remains the leading cause of death in women worldwide. New technologies including oncolytic virus therapies, virus, and phage display are among the most powerful and advanced methods that have emerged in recent years with potential applications in cancer prevention and treatment. Oncolytic virus therapy is an interesting strategy for cancer treatment. Presently, a number of viruses from different virus families are under laboratory and clinical investigation as oncolytic therapeutics. Oncolytic viruses (OVs) have been shown to be able to induce and initiate a systemic antitumor immune response. The possibility of application of a multimodal therapy using a combination of the OV therapy with immune checkpoint inhibitors and cancer antigen vaccination holds a great promise in the future of cancer immunotherapy. Display of immunologic peptides on bacterial viruses (bacteriophages) is also increasingly being considered as a new and strong cancer vaccine delivery strategy. In phage display immunotherapy, a peptide or protein antigen is presented by genetic fusions to the phage coat proteins, and the phage construct formulation acts as a protective or preventive vaccine against cance...Continue Reading

References

Mar 1, 1980·Journal of Ultrastructure Research·P Granboulan
Jun 1, 1993·Trends in Biotechnology·W H Luyten, J E Leysen
May 3, 1996·Journal of Molecular Biology·M E Cerritelli, F W Studier
Aug 10, 2000·Nature Biotechnology·P De BerardinisJ Guardiola
Mar 10, 2001·European Journal of Immunology·M Sioud, M H Hansen
Mar 9, 2002·Current Pharmaceutical Biotechnology·Yum L Yip, Robyn L Ward
Mar 28, 2002·Human Gene Therapy·Kara L NormanPatrick W K Lee
Sep 19, 2003·Advances in Protein Chemistry·Mario E CerritelliAlasdair C Steven
Feb 3, 2004·Journal of Receptor and Signal Transduction Research·Michael Szardenings
Oct 3, 2006·Nature Genetics·Jason S CarrollMyles Brown
Sep 13, 2007·Molecular Therapy : the Journal of the American Society of Gene Therapy·Minna ErikssonAkseli Hemminki
Feb 8, 2008·Breast Cancer Research and Treatment·Kathryn A SkeldingDarren R Shafren
Jun 17, 2008·Nature Reviews. Microbiology·Roberto CattaneoMichael A Barry
Oct 8, 2008·International Journal of Cancer. Journal International Du Cancer·Kalle AndreassonTorbjörn Ramqvist
Nov 1, 2008·The Prostate·Pavlos MsaouelEvanthia Galanis
Feb 11, 2009·Current Topics in Microbiology and Immunology·S J Russell, K W Peng
Jul 1, 2009·Breast Cancer Research and Treatment·Ghaffar MuharramDominique Stehelin
Aug 18, 2009·Expert Review of Proteomics·Caroline DesmetzJerome Solassol
Dec 8, 2009·Cancer Cell·Kazuki N SugaharaErkki Ruoslahti
Feb 23, 2010·Chemical Reviews·Susan L Deutscher
Apr 8, 2010·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Takuya YamashitaKazuo Maruyama
Jan 1, 2008·Clinical Medicine. Oncology·Robin J PrestwichAlan Melcher
Jan 12, 2012·Virology Journal·Irshad Ul HaqIshtiaq Qadri
Mar 8, 2012·Future Microbiology·Dmitriy Zamarin, Peter Palese
Jul 12, 2012·Nature Biotechnology·Stephen J RussellJohn C Bell
Oct 3, 2012·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Stanislav SokolenkoMarc G Aucoin
Mar 27, 2013·Methods in Molecular Biology·Vincent G L PostisStephen A Baldwin
Apr 16, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A MilaniG Valabrega
May 4, 2013·Applied Microbiology and Biotechnology·Jessica NicastroRoderick Slavcev
Aug 21, 2013·Human Vaccines & Immunotherapeutics·Lingxiao ZhaoHua Cong
Jan 21, 2014·Applied Microbiology and Biotechnology·Jessica NicastroRoderick A Slavcev
Feb 18, 2014·Biochemical and Biophysical Research Communications·Xiaoyong DaiQing Zheng
Mar 29, 2014·Methods in Molecular Biology·Hiroshi Nakashima, E Antonio Chiocca
Jul 8, 2014·Trends in Biotechnology·Loek J EggermontCarl G Figdor
Aug 27, 2014·Molecular Therapy : the Journal of the American Society of Gene Therapy·Christine E EngelandGuy Ungerechts

❮ Previous
Next ❯

Citations

Jan 10, 2020·Archivum Immunologiae Et Therapiae Experimentalis·Atefeh ArabJavad Behravan
Oct 24, 2019·Journal of Cellular Physiology·Atefeh Razazan, Javad Behravan
Jan 29, 2020·Bioengineering & Translational Medicine·Krystina L Hess, Christopher M Jewell
Feb 23, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Martina GoracciSerena Marchiò
Apr 8, 2021·Immunotherapy·Ramon Andrade de MelloJosé Antonio Silva
Jun 22, 2021·Frontiers in Bioengineering and Biotechnology·Yang LiShouju Wang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.

Cancer Vaccines

Cancer vaccines are vaccines that either treat existing cancer or prevent development of a cancer.

Breast Cancer: Therapeutic Approaches

Several different therapeutic approaches are used to treat breast cancer. These include chemotherapy, hormonal therapy, targeted therapy, and Immunotherapy. Discover the latest research on breast cancer therapeutic approaches here.

Cell Checkpoints & Regulators

Cell cycle checkpoints are a series of complex checkpoint mechanisms that detect DNA abnormalities and ensure that DNA replication and repair are complete before cell division. They are primarily regulated by cyclins, cyclin-dependent kinases, and the anaphase-promoting complex/cyclosome. Here is the latest research.

Related Papers

Nature Reviews. Cancer
Brian Dennis LichtyJohn C Bell
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
Clare Y Slaney, Phillip K Darcy
Current Oncology Reports
Claire-Audrey Y BayanYvonne M Saenger
© 2022 Meta ULC. All rights reserved