The Visceral Sensitivity Index: development and validation of a gastrointestinal symptom-specific anxiety scale

Alimentary Pharmacology & Therapeutics
J S LabusB D Naliboff

Abstract

Anxiety related to gastrointestinal sensations, symptoms or the contexts in which these may occur is thought to play a significant role in the pathophysiology as well as in the health outcomes of patients with irritable bowel syndrome. To develop a valid and reliable psychometric instrument that measures gastrointestinal symptom-specific anxiety. External and internal expert panels as well as a patient focus group evaluated a large pool of potential item stems gathered from the psychological and gastrointestinal literature. Potential scale items were then administered to 96 patients diagnosed with irritable bowel syndrome along with a set of validating questionnaires. Final item selection was based upon rigorous empirical criteria and the psychometric properties of the final scale were examined. A final unidimensional 15-item scale, the Visceral Sensitivity Index, demonstrated excellent reliability as well as good content, convergent, divergent and predictive validity. The findings suggest that the Visceral Sensitivity Index is a reliable, valid measure of gastrointestinal symptom-specific anxiety that may be useful for clinical assessment, treatment outcome studies, and mechanistic studies of the role of symptom-related anxiet...Continue Reading

References

Aug 1, 1990·Gastroenterology·R S Sandler
Jan 1, 1986·Behaviour Research and Therapy·S ReissR J McNally
Jun 1, 1983·Acta Psychiatrica Scandinavica·A S Zigmond, R P Snaith
Nov 15, 1995·Annals of Internal Medicine·D A DrossmanM A Barreiro
Sep 1, 1995·Behaviour Research and Therapy·G J Asmundson, G R Norton
Nov 1, 1996·Behaviour Research and Therapy·L M McCrackenC L Carnrike
Mar 1, 1997·Journal of Anxiety Disorders·S Reiss
Jun 5, 1998·Behaviour Research and Therapy·S Taylor, B J Cox
Aug 26, 1998·Psychosomatic Medicine·B B TonerD Akman
Dec 22, 1998·Journal of Psychosomatic Research·B D NaliboffE A Mayer
Feb 13, 1999·Clinical Psychology Review·G J AsmundsonG R Norton
May 10, 1985·Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie·T KrupaJ Thornton
Dec 10, 1999·The American Journal of Medicine·E A Mayer
Sep 13, 2000·Gastroenterology·I M GralnekE A Mayer
Mar 20, 2001·American Journal of Physiology. Gastrointestinal and Liver Physiology·E A MayerS V Coutinho
Apr 4, 2002·Psychological Methods·David P MacKinnonVirgil Sheets
Jul 2, 2002·Journal of Consulting and Clinical Psychology·Edward B Blanchard, Lisa Scharff
Sep 15, 2004·Archives of Internal Medicine·Brennan M R SpiegelBruce Naliboff

❮ Previous
Next ❯

Citations

Oct 26, 2012·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Nuno Bravo FerreiraDavid T Gillanders
Apr 13, 2013·Behaviour Research and Therapy·Jeffrey M LacknerDarren M Brenner
Mar 5, 2008·Evidence-based Complementary and Alternative Medicine : ECAM·Bruce D NaliboffLobsang Rapgay
Jul 30, 2009·BMC Complementary and Alternative Medicine·Susan A GaylordJohn Douglas Mann
Jul 19, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jui-Yang HongEmeran A Mayer
Mar 1, 2012·World Journal of Gastroenterology : WJG·Teodora Surdea-BlagaDan L Dumitrascu
Dec 18, 2013·The American Journal of Gastroenterology·Puja KhannaBrennan Mr Spiegel
Nov 26, 2010·Annual Review of Medicine·Emeran A Mayer, Kirsten Tillisch
May 9, 2014·Digestive Diseases and Sciences·Erica CohenBrennan Spiegel
Sep 10, 2014·The American Journal of Gastroenterology·Brennan M R SpiegelDinesh Khanna
Oct 24, 2015·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·B Le NevéM Simrén
Nov 6, 2015·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·J TackL Van Oudenhove
Dec 20, 2011·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Kara BradfordLin Chang
Apr 7, 2010·Behaviour Research and Therapy·Brjánn LjótssonGerhard Andersson
Oct 24, 2007·Gastroenterology Clinics of North America·Elizabeth J Videlock, Lin Chang
Aug 4, 2009·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·E A MayerI Tracey
Feb 7, 2007·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·P AnandL van Oudenhove
Oct 20, 2010·Alimentary Pharmacology & Therapeutics·B M R SpiegelL Chang
May 28, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·A RubioB Bonaz
Apr 1, 2015·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·M E RiehlL Keefer
Apr 7, 2010·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·P JerndalM Simrén
Sep 16, 2009·Alimentary Pharmacology & Therapeutics·B SpiegelL Chang
Sep 12, 2009·Alimentary Pharmacology & Therapeutics·H R CarruthersP J Whorwell
Jun 13, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·S LudidiA Masclee
Aug 21, 2015·Alimentary Pharmacology & Therapeutics·Z MujagicA A M Masclee
Jan 19, 2010·Journal of Behavior Therapy and Experimental Psychiatry·Brjánn LjótssonNils Lindefors
Apr 12, 2016·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·S H ParkL Chang
Mar 31, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·I BjörkmanM Simrén
Jun 20, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·C S HubbardJ S Labus

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.