The weight of the prostate gland is an excellent surrogate for gland volume

Histopathology
Murali Varma, John M Morgan

Abstract

Prostate gland volume is generally assessed by transrectal ultrasound examination or magnetic resonance imaging at the time of prostatic biopsy or pre-brachytherapy planning. The volume is most commonly measured using the formula, prostate volume = height x width x length x pi/6, which is derived considering the gland as ellipsoid. There are conflicting data regarding the accuracy of this method, with most studies comparing this calculated volume with that measured radiologically using planimetry with summation of sequential area measurements. The aim was to determine the relationship between prostate gland volume and weight. The accuracy of prostate gland volume calculated from three-dimensional measurements of the gland in 20 radical prostatectomy specimens relative to the true gland volume determined using water displacement was prospectively evaluated. Since volume measurement by water displacement is not practical in routine practice, the relationship between prostate weight and volume was also evaluated. Our findings indicate that the calculated gland volume consistently underestimates the true volume. The volume of the prostate gland (in cm(3)) very closely correlates with its weight (in g). The weight of the prostate gl...Continue Reading

References

May 1, 1991·The Journal of Urology·M K Terris, T A Stamey
Nov 1, 1989·British Journal of Urology·D R JonesW B Peeling
Mar 11, 2003·Prostate Cancer and Prostatic Diseases·L M EriL L Håheim
Mar 21, 2003·Virchows Archiv : an International Journal of Pathology·Rodolfo MontironiTheodorus Kwast
Aug 4, 2007·Virchows Archiv : an International Journal of Pathology·Jonathan I EpsteinChristopher Otis
Aug 21, 2007·Human Pathology·Jonathan I EpsteinUNKNOWN Association of Directors of Anatomic and Surgical Pathology
Dec 14, 2007·The Journal of Urology·Esequiel RodriguezThomas E Ahlering

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Citations

Apr 4, 2012·BJU International·Matthew K H HongNiall M Corcoran
Feb 8, 2020·Histopathology·Murali VarmaDaniel M Berney
Jul 20, 2020·International Journal of Clinical Practice·Rotimi A DavidChigozie I Onyeze
Aug 27, 2015·International Journal of Surgical Pathology·George A TjionasOleksandr N Kryvenko
Sep 29, 2020·SAGE Open Medicine·Hajime TsuboiHiroshi Ikegaya
May 13, 2021·World Journal of Urology·Nicholas E BoxallTevita F Aho

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