The Wheat Mediator Subunit TaMED25 Interacts with the Transcription Factor TaEIL1 to Negatively Regulate Disease Resistance against Powdery Mildew

Plant Physiology
Jie LiuJiaqiang Sun

Abstract

Powdery mildew, caused by the biotrophic fungal pathogen Blumeria graminis f. sp. tritici, is a major limitation for the production of bread wheat (Triticum aestivum). However, to date, the transcriptional regulation of bread wheat defense against powdery mildew remains largely unknown. Here, we report the function and molecular mechanism of the bread wheat Mediator subunit 25 (TaMED25) in regulating the bread wheat immune response signaling pathway. Three homoalleles of TaMED25 from bread wheat were identified and mapped to chromosomes 5A, 5B, and 5D, respectively. We show that knockdown of TaMED25 by barley stripe mosaic virus-induced gene silencing reduced bread wheat susceptibility to the powdery mildew fungus during the compatible plant-pathogen interaction. Moreover, our results indicate that MED25 may play a conserved role in regulating bread wheat and barley (Hordeum vulgare) susceptibility to powdery mildew. Similarly, bread wheat ETHYLENE INSENSITIVE3-LIKE1 (TaEIL1), an ortholog of Arabidopsis (Arabidopsis thaliana) ETHYLENE INSENSITIVE3, negatively regulates bread wheat resistance against powdery mildew. Using various approaches, we demonstrate that the conserved activator-interacting domain of TaMED25 interacts phys...Continue Reading

Citations

May 20, 2017·Critical Reviews in Biochemistry and Molecular Biology·Naveen MalikAkhilesh Tyagi
Jun 25, 2017·Annual Review of Phytopathology·Matthias L BerensKenichi Tsuda
Dec 28, 2017·Journal of Experimental Botany·Tim CrawfordÅsa Strand
Nov 9, 2019·The Plant Journal : for Cell and Molecular Biology·Naveen MalikAkhilesh K Tyagi
May 16, 2017·The Plant Journal : for Cell and Molecular Biology·Yunwei ZhangDingzhong Tang
Sep 25, 2017·Molecular Plant Pathology·Baohong ZouJian Hua
Sep 19, 2018·Journal of Integrative Plant Biology·Hong LiuXueyong Zhang
Jul 1, 2017·Frontiers in Plant Science·Kemal Kazan
Mar 30, 2021·Plant Science : an International Journal of Experimental Plant Biology·Go SuzukiKenji Gomi

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