The where, when, and how of organelle acidification by the yeast vacuolar H+-ATPase

Microbiology and Molecular Biology Reviews : MMBR
Patricia M Kane

Abstract

All eukaryotic cells contain multiple acidic organelles, and V-ATPases are central players in organelle acidification. Not only is the structure of V-ATPases highly conserved among eukaryotes, but there are also many regulatory mechanisms that are similar between fungi and higher eukaryotes. These mechanisms allow cells both to regulate the pHs of different compartments and to respond to changing extracellular conditions. The Saccharomyces cerevisiae V-ATPase has emerged as an important model for V-ATPase structure and function in all eukaryotic cells. This review discusses current knowledge of the structure, function, and regulation of the V-ATPase in S. cerevisiae and also examines the relationship between biosynthesis and transport of V-ATPase and compartment-specific regulation of acidification.

References

Mar 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·T NoumiN Nelson
Aug 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·J Nakajima-ShimadaY Anraku
Sep 14, 1990·Science·J GuastellaB I Kanner
May 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·H Nelson, N Nelson
Aug 1, 1990·The Journal of Cell Biology·L A VallsT H Stevens
Sep 1, 1990·Microbiological Reviews·D J KlionskyS D Emr
Nov 30, 1987·Biochemical and Biophysical Research Communications·Y Moriyama, N Nelson
Aug 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·M MandelN Nelson
Mar 1, 1989·Trends in Biochemical Sciences·N Nelson, L Taiz
Sep 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·J P GogartenT Oshima
Jan 1, 1986·Annual Review of Biochemistry·I MellmanA Helenius
Jan 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·E J BowmanB J Bowman
Jan 17, 1995·Proceedings of the National Academy of Sciences of the United States of America·H NelsonN Nelson
Mar 10, 1995·The Journal of Biological Chemistry·J P SumnerH Wieczorek
Feb 15, 1994·European Journal of Biochemistry·S O SørensenJ R Winther
Aug 23, 1996·The Journal of Biological Chemistry·R GräfH Wieczorek
Sep 13, 1996·The Journal of Biological Chemistry·X H LengM Forgac
Dec 15, 1996·Experientia·N Nelson, D J Klionsky
Oct 23, 1997·The Journal of Biological Chemistry·J J TomashekD J Klionsky
Dec 31, 1997·Molecular and Cellular Biology·C J BonangelinoL S Weisman

❮ Previous
Next ❯

Citations

Sep 8, 2010·Cellular and Molecular Life Sciences : CMLS·Alexander V ZhdanovDmitri B Papkovsky
Jan 7, 2009·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Giancarlo Lopez-MartinezDavid L Denlinger
Nov 21, 2007·Pflügers Archiv : European journal of physiology·Ayana HintonMichael Forgac
Mar 6, 2008·Pflügers Archiv : European journal of physiology·Shai Saroussi, Nathan Nelson
Nov 15, 2007·Journal of Bioenergetics and Biomembranes·Patricia M Kane
Nov 28, 2007·Journal of Bioenergetics and Biomembranes·Jie QiMichael Forgac
Jan 25, 2008·Journal of Bioenergetics and Biomembranes·Yoh WadaNobuyuki Kawamura
May 11, 2010·Biochemistry·Masashi ToeiMichael Forgac
Oct 4, 2007·Nature Reviews. Molecular Cell Biology·Michael Forgac
Jan 19, 2010·Proceedings of the National Academy of Sciences of the United States of America·Wilson C Y Lau, John L Rubinstein
Jun 8, 2010·The Journal of Biological Chemistry·Rodrigo AlzamoraNúria M Pastor-Soler
Jun 1, 2010·The Journal of Biological Chemistry·Theodore T Diakov, Patricia M Kane
Sep 15, 2010·The Journal of Biological Chemistry·Norbert KartnerMorris F Manolson
Jan 18, 2011·The Journal of Biological Chemistry·Chunjuan Huang, Amy Chang
Jun 13, 2012·The Journal of Biological Chemistry·Yanqing XuBarry I Posner
Jun 15, 2007·The Journal of Biological Chemistry·Jie Qi, Michael Forgac
Sep 28, 2007·The Journal of Biological Chemistry·Yanru WangMichael Forgac
Dec 25, 2007·The Journal of Biological Chemistry·Kevin C Jefferies, Michael Forgac
May 27, 2008·The Journal of Biological Chemistry·Gloria A Martínez-Muñoz, Patricia Kane
May 22, 2008·The Journal of Biological Chemistry·Jie Qi, Michael Forgac
Aug 19, 2008·The Journal of Biological Chemistry·Andrew R Flannery, Tom H Stevens
Oct 22, 2008·The Journal of Biological Chemistry·Sarah Bond, Michael Forgac
Oct 29, 2008·The Journal of Biological Chemistry·Zhenyu ZhangStephan Wilkens
Mar 21, 2009·The Journal of Biological Chemistry·Heba DiabPatricia M Kane
Jul 10, 2013·The Journal of Cell Biology·Alexandre Toulmay, William A Prinz
Oct 20, 2010·Omics : a Journal of Integrative Biology·Nuno P MiraIsabel Sá-Correia
Jul 27, 2007·Molecular Biology of the Cell·Tonie L BaarsAndreas Mayer
Sep 19, 2008·Molecular Biology of the Cell·Shuliang ChenMiriam L Greenberg
Sep 19, 2008·Molecular Biology of the Cell·Margret RyanTom H Stevens
Jan 1, 2009·Molecular Biology of the Cell·Vikram C AnandGregory S Payne
Oct 15, 2010·Molecular Biology of the Cell·Rosie Dawaliby, Andreas Mayer
Jun 30, 2009·Current Opinion in Nephrology and Hypertension·Katherine G Blake-Palmer, Fiona E Karet
Dec 26, 2012·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Hendrik Sielaff, Michael Börsch
Mar 6, 2007·Plant Physiology·Senthilkumar PadmanabanHeven Sze

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.