The WHO classification of pulmonary hypertension: A case-based imaging compendium.

Pulmonary Circulation
John J RyanStephen L Archer

Abstract

Pulmonary hypertension (PH) is defined as a resting mean pulmonary artery pressure greater than 25 mmHg. The World Health Organization (WHO) classifies PH into five categories. The WHO nomenclature assumes shared histology and pathophysiology within categories and implies category-specific treatment. Imaging of the heart and pulmonary vasculature is critical to assigning a patient's PH syndrome to the correct WHO category and is also important in predicting outcomes. Imaging studies often reveal that the etiology of PH in a patient reflects contributions from several categories. Overlap between Categories 2 and 3 (left heart disease and lung disease) is particularly common, reflecting shared risk factors. Correct classification of PH patients requires the combination of standard imaging (chest roentgenograms, ventilation-perfusion scans, echocardiography, and the 12-lead electrocardiogram) and advanced imaging (computed tomography, cardiac magnetic resonance imaging, and positron emission tomography). Despite the value of imaging, cardiac catheterization remains the gold standard for quantification of hemodynamics and is required before initiation of PH-specific therapy. These cases illustrate the use of imaging in classifying ...Continue Reading

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Citations

Nov 28, 2013·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Carina Teixeira-Mendonça, Tiago Henriques-Coelho
Oct 17, 2012·American Journal of Respiratory and Critical Care Medicine·Thenappan ThenappanStephen L Archer
Jul 20, 2014·Seminars in Perinatology·Sarah G Običan, Kirsten L Cleary
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Apr 4, 2015·The Canadian Journal of Cardiology·Eduardo BossoneMelvyn Rubenfire
Apr 4, 2015·The Canadian Journal of Cardiology·Ana Olga MocumbiKaren Sliwa
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Jul 8, 2017·Antioxidants·David J R FultonScott A Barman
Jan 10, 2016·American Journal of Physiology. Lung Cellular and Molecular Physiology·Danielle R BrunsLori A Walker

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Methods Mentioned

BETA
X-ray
dissection
biopsy

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