The Wound Healing Potential of Aspilia africana (Pers.) C. D. Adams (Asteraceae)

Evidence-based Complementary and Alternative Medicine : ECAM
Richard KomakechYoungmin Kang

Abstract

Wounds remain one of the major causes of death worldwide. Over the years medicinal plants and natural compounds have played an integral role in wound treatment. Aspilia africana (Pers.) C. D. Adams which is classified among substances with low toxicity has been used for generations in African traditional medicine to treat wounds, including stopping bleeding even from severed arteries. This review examined the potential of the extracts and phytochemicals from A. africana, a common herbaceous flowering plant which is native to Africa in wound healing. In vitro and in vivo studies have provided strong pharmacological evidences for wound healing effects of A. africana-derived extracts and phytochemicals. Singly or in synergy, the different bioactive phytochemicals including alkaloids, saponins, tannins, flavonoids, phenols, terpenoids, β-caryophyllene, germacrene D, α-pinene, carene, phytol, and linolenic acid in A. africana have been observed to exhibit a very strong anti-inflammatory, antimicrobial, and antioxidant activities which are important processes in wound healing. Indeed, A. africana wound healing ability is furthermore due to the fact that it can effectively reduce wound bleeding, hasten wound contraction, increase the ...Continue Reading

References

May 1, 1993·Proceedings of the Society for Experimental Biology and Medicine·B H Porras-ReyesT A Mustoe
Apr 9, 2001·Clinical Microbiology Reviews·P G BowlerD G Armstrong
Mar 21, 2002·Journal of Agricultural and Food Chemistry·Ji-Young LeeDong-Hwa Shin
Jun 14, 2006·British Journal of Pharmacology·Yoshiyuki KimuraMasahiro Sakanaka
Sep 5, 2006·Journal of Ethnopharmacology·C O OkoliO Erojikwe
Jul 12, 2007·BMC Complementary and Alternative Medicine·C O OkoliA S Okoli
Jul 7, 2009·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·M J ChavanD B Shinde
May 5, 2010·Pakistan Journal of Biological Sciences : PJBS·T O OyesolaC S Okoye
Jul 27, 2010·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sreenivasan SasidharanRajoo Amala
Jul 1, 2011·Evidence-based Complementary and Alternative Medicine : ECAM·Rupesh ThakurSardul Singh Sandhu
Sep 24, 2011·Evidence-based Complementary and Alternative Medicine : ECAM·Ibrahim TumenEsra Küpeli Akkol
Jan 22, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rita de Cássia da Silveira e SáDamião Pergentino de Sousa
Jan 25, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Liang XiongOu Dai
Mar 20, 2013·BioMed Research International·R GeethalakshmiD V L Sarada
Sep 1, 2011·Journal of Ginseng Research·Young Soo KimChun Sik Bae
Aug 1, 2013·Indian Journal of Pharmaceutical Sciences·Z ParveenK Shahzad
Oct 10, 2013·Fundamental & Clinical Pharmacology·Renan O SilvaJand Venes R Medeiros
Nov 29, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Faraidoon HaghdoostShaghayegh Haghjooy Javanmard
Jul 6, 2014·Skin Pharmacology and Physiology·Nader PazyarAmir Feily
Mar 10, 2015·Expert Review of Anti-infective Therapy·Raffaele SerraStefano de Franciscis
Jul 2, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Saad S DahhamAmin M S A Majid
Aug 22, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Loh Teng Hern TanBey Hing Goh
Aug 27, 2015·Journal of Pharmaceutical Sciences·Joshua Boateng, Ovidio Catanzano
Sep 10, 2015·The Journal of Nutritional Biochemistry·Ram ReifenAbraham Nyska
Nov 10, 2015·Journal of Ethnopharmacology·Christian AgyareTheresa Appiah
Jan 23, 2016·PeerJ·Quentin M NunesDavid G Fernig
Jun 1, 2005·Malawi Medical Journal : the Journal of Medical Association of Malawi·L Chokotho, E van Hasselt
Nov 10, 2016·Anais Brasileiros De Dermatologia·Ana Cristina de Oliveira GonzalezAlena Ribeiro Alves Peixoto Medrado
Jan 4, 2017·Burns : Journal of the International Society for Burn Injuries·Xiaowen SuKun Li
Jul 29, 2017·BioImpacts : BI·Keyvan YousefiFatemeh Fathiazad
Mar 2, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Cristina M Pérez ZamoraMaría B Nuñez

❮ Previous
Next ❯

Citations

Aug 1, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Denis OkelloYoungmin Kang
Mar 19, 2021·Saudi Journal of Biological Sciences·A Al-KhulaidiA Al-Namazi
Aug 3, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Solome Melkamu TaddeseTezera Jemere Aragaw

❮ Previous
Next ❯

Software Mentioned

Scopus
Google Scholar

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.