PMID: 8589515Aug 1, 1995Paper

The X-linked methylated DNA binding protein, Mecp2, is subject to X inactivation in the mouse

Mammalian Genome : Official Journal of the International Mammalian Genome Society
D A AdlerC M Disteche

Abstract

DNA methylation at the promoter region of X-linked genes is associated with the maintenance of X inactivation in mammals. One of the methylated DNA binding proteins, MECP2, that binds to methylated bases in DNA is encoded by a gene (Mecp2) located on the mouse X Chromosome (Chr). To determine whether this gene was expressed from the inactive X Chr, and X-autosome translocation (T(X;16)16H) system in which expression from the Mecp2 allele on the inactive X Chr could be assayed was used. Results from these experiments indicate that Mecp2 is subject to X inactivation in mouse.

References

Jun 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·D A AdlerC M Disteche
Jan 1, 1993·Mammalian Genome : Official Journal of the International Mammalian Genome Society·S D BrownG E Herman
Jan 1, 1964·Cytogenetics·M F LYONS OHNO

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Citations

Jul 12, 2002·Mental Retardation and Developmental Disabilities Research Reviews·Sara HammerCarolyn Schanen
Jul 12, 2002·Mental Retardation and Developmental Disabilities Research Reviews·Ignatia B Van den Veyver, Huda Y Zoghbi
Jul 1, 1996·Mammalian Genome : Official Journal of the International Mammalian Genome Society·M D'EspositoS D Brown
Sep 30, 2008·Nucleic Acids Research·Jasmine SinghDavid Ravine
Jan 7, 2005·Journal of Medical Genetics·L S WeavingJ Christodoulou
Aug 6, 2013·Cellular and Molecular Life Sciences : CMLS·Bing Yao, Peng Jin
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Jul 23, 2003·Human Mutation·Gabriel Miltenberger-Miltenyi, Franco Laccone
May 3, 2006·Current Opinion in Genetics & Development·Brunella Franco, Andrea Ballabio
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Oct 18, 2005·Journal of Child Neurology·Peter Huppke, Jutta Gärtner
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Jul 25, 2018·Nature Communications·Ivan N BolotovOleg S Pokrovsky
Jul 19, 2020·Human Molecular Genetics·Deivid Carvalho RodriguesJames Ellis
Sep 25, 2003·Genetics·Sabine SchüttReinald H Fundele

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