The yeast peroxisomal adenine nucleotide transporter: characterization of two transport modes and involvement in DeltapH formation across peroxisomal membranes

The Biochemical Journal
Francesco Massimo LasorsaLuigi Palmieri

Abstract

The yeast peroxisomal adenine nucleotide carrier, Ant1p, was shown to catalyse unidirectional transport in addition to exchange of substrates. In both transport modes, proton movement occurs. Nucleotide hetero-exchange is H+-compensated and electroneutral. Furthermore, microscopic fluorescence imaging of a pH-sensitive green fluorescent protein targeted to peroxisomes shows that Ant1p is involved in the formation of a DeltapH across the peroxisomal membrane, acidic inside.

References

Feb 1, 1987·Archives of Microbiology·K NicolayW Harder
Aug 1, 1993·FEMS Microbiology Reviews·G J SulterM Veenhuis
Oct 1, 1996·The Journal of Cell Biology·R Erdmann, G Blobel
Jan 6, 2000·Nature Cell Biology·T B DansenE H Pap
Jun 17, 2000·Biochimica Et Biophysica Acta·E H Hettema, H F Tabak
Oct 20, 2001·The Journal of Biological Chemistry·A JankowskiS Grinstein
Mar 5, 2004·The Journal of Biological Chemistry·Angelo VozzaFerdinando Palmieri

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Citations

Aug 17, 2005·Nature Reviews. Molecular Cell Biology·Ralf Erdmann, Wolfgang Schliebs
Mar 28, 2008·The Journal of Biological Chemistry·Francesco Massimo LasorsaFerdinando Palmieri
Jun 8, 2006·Annual Review of Biochemistry·Ronald J A Wanders, Hans R Waterham
Apr 9, 2009·PloS One·Aare RokkaJ Kalervo Hiltunen
Jan 8, 2014·Proceedings of the National Academy of Sciences of the United States of America·Angelo VozzaGiuseppe Fiermonte
Jan 6, 2011·Cellular and Molecular Life Sciences : CMLS·Javier TrabaAraceli del Arco
Dec 22, 2011·The Biochemical Journal·Gennaro AgrimiFerdinando Palmieri
Jan 13, 2012·The Biochemical Journal·Luis A Luévano-MartínezSalvador Uribe-Carvajal
Oct 3, 2006·Biochimica Et Biophysica Acta·Hanspeter Rottensteiner, Frederica L Theodoulou
Jan 18, 2006·FEBS Letters·Frederica L TheodoulouAlison Baker
Oct 25, 2007·Biochemical Society Transactions·R J A Wanders, J C Komen
Dec 19, 2006·The Biochemical Journal·Wouter F VisserRonald J A Wanders
Mar 26, 2008·The Journal of Biological Chemistry·Ilaria DragoTullio Pozzan
Aug 12, 2005·Molecular Membrane Biology·Paul A M MichelsVéronique Hannaert
Jan 29, 2021·Frontiers in Cell and Developmental Biology·Serhii ChornyiHans R Waterham
Oct 19, 2006·Biochimica Et Biophysica Acta·Vasily D Antonenkov, J Kalervo Hiltunen
Oct 24, 2006·Biochimica Et Biophysica Acta·Markus KunzeAndreas Hartig
Mar 23, 2011·Biochimica Et Biophysica Acta·Rick OrijGertien J Smits
Dec 31, 2011·Biochimica Et Biophysica Acta·Vasily D Antonenkov, J Kalervo Hiltunen

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