The Yersinia pestis Rcs phosphorelay inhibits biofilm formation by repressing transcription of the diguanylate cyclase gene hmsT.

Journal of Bacteriology
Yi-Cheng SunCreg Darby

Abstract

Yersinia pestis, which causes bubonic plague, forms biofilms in fleas, its insect vectors, as a means to enhance transmission. Biofilm development is positively regulated by hmsT, encoding a diguanylate cyclase that synthesizes the bacterial second messenger cyclic-di-GMP. Biofilm development is negatively regulated by the Rcs phosphorelay signal transduction system. In this study, we show that Rcs-negative regulation is accomplished by repressing transcription of hmsT.

References

Jul 1, 1991·Clinical Microbiology Reviews·R R Brubaker
Apr 7, 1999·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·R A SmegoH J Koornhof
Apr 29, 1999·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·H J KoornhofM Nicol
Nov 26, 1999·Proceedings of the National Academy of Sciences of the United States of America·M AchtmanE Carniel
Jun 1, 2000·Proceedings of the National Academy of Sciences of the United States of America·K A Datsenko, B L Wanner
May 17, 2002·Nature·Creg DarbyStanley Falkow
Jul 17, 2003·Molecular Microbiology·Anne Francez-CharlotKaymeuang Cam
Mar 5, 2004·Journal of Bacteriology·Robert D PerryJacqueline D Fetherston
Jul 24, 2004·The Journal of Infectious Diseases·Clayton O JarrettB Joseph Hinnebusch
Sep 11, 2004·Proceedings of the National Academy of Sciences of the United States of America·P S G ChainE Garcia
Dec 16, 2004·Proceedings of the National Academy of Sciences of the United States of America·Mark AchtmanPaul Keim
Sep 13, 2005·Annual Review of Microbiology·Nadim Majdalani, Susan Gottesman
Jan 27, 2006·FEMS Microbiology Letters·Alexander G Bobrov, Robert D Perry
Mar 29, 2006·Proceedings of the National Academy of Sciences of the United States of America·Florent SebbaneB Joseph Hinnebusch
Nov 1, 2006·Microbiology·Stanislav FormanRobert D Perry
Apr 10, 2007·Lancet·Michael B Prentice, Lila Rahalison
May 22, 2007·Applied and Environmental Microbiology·Roman G GerlachMichael Hensel
Mar 15, 2008·Trends in Microbiology·Creg Darby
Jun 5, 2008·Proceedings of the National Academy of Sciences of the United States of America·Yi-Cheng SunCreg Darby

❮ Previous
Next ❯

Citations

Nov 20, 2012·Journal of Bacteriology·Violeta ZorraquinoCristina Solano
Jan 4, 2013·PloS One·Fengjun SunRuifu Yang
Feb 10, 2016·Microbiological Research·Chun-Yang ChangWhei-Fen Wu
Mar 15, 2016·Frontiers in Cellular and Infection Microbiology·Shiyun ChenMatthew S Francis
May 17, 2014·Cell Host & Microbe·Yi-Cheng SunB Joseph Hinnebusch
Oct 25, 2016·Protein Science : a Publication of the Protein Society·Ekaterina V FilippovaWayne F Anderson
Jan 13, 2018·Glycobiology·Ewa JankowskaJohn F Cipollo
May 11, 2016·Infection and Immunity·B Joseph HinnebuschYi-Cheng Sun
Apr 6, 2018·Clinical Microbiology Reviews·Maria MaganaGeorge P Tegos
Sep 10, 2017·Annual Review of Microbiology·B Joseph HinnebuschDavid M Bland
Nov 2, 2017·Frontiers in Microbiology·Xiao-Peng Guo, Yi-Cheng Sun
Oct 4, 2018·Frontiers in Cellular and Infection Microbiology·Jeffrey K SchachterleDavid L Erickson
Nov 8, 2020·Applied and Environmental Microbiology·Xuewei PanZhiming Rao
Feb 7, 2021·Biomolecules·B Joseph HinnebuschDavid M Bland

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biofilms

Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.