The Yokohama system for reporting directly sampled endometrial cytology: The quest to develop a standardized terminology

Diagnostic Cytopathology
Franco FulcinitiYasuo Hirai

Abstract

The main purpose of directly sampled endometrial cytology is to detect invasive endometrial malignancies. With this principle in mind, The Yokohama System (TYS) Working Group, composed of cytopathologists, surgical pathologists, and gynecologic oncologists met at the 2016 International Congress of Cytology, Yokohama, with the aim to publish a standardized reporting system inclusive of specific diagnostic categories and cytomorphologic criteria for uniform and reliable diagnosis of endometrial malignancies on directly sampled endometrial samples. The diagnostic cytopathologic criteria previously published in the literature by the Japanese and Greek working group on endometrial cytology (Yanoh et al. [2012] Acta Cytol. 56:233; Margari et al. [2016] Diagn Cytopathol. 44:888-901) were critically reviewed with the aim of correlating the diagnostic classes to well defined risk categories for endometrial carcinoma (EC). Moreover, two classes of "atypical" endometrial cells were correlated respectively to a low- and high risk group. Some methodological suggestions for the application of ancillary special technologies to liquid based samples were also given. The TYS group conceived a new Bethesda-style classification for directly sample...Continue Reading

References

Jun 8, 2000·Journal of the National Cancer Institute·G L MutterC Eng
Dec 7, 2007·Obstetrics and Gynecology Clinics of North America·Pamela T Soliman, Karen Lu
Sep 17, 2008·Oncogene·Y Yin, W H Shen
Dec 17, 2008·Cancer Control : Journal of the Moffitt Cancer Center·Nisha BansalRobert M Wenham
Mar 28, 2009·The Journal of Molecular Diagnostics : JMD·Maria Simona PinoDaniel C Chung
Oct 29, 2009·Journal of Hematology & Oncology·Ruirong YuanDavid Lebwohl
Jan 25, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Filip JankuRazelle Kurzrock
Jul 19, 2012·Diagnostic Cytopathology·Alessia Di LoritoFernando Carlos Schmitt
May 3, 2013·Nature·Cyriac KandothDouglas A Levine
Jul 19, 2013·Cancer Management and Research·P PathirajaK Haldar
Sep 18, 2014·The American Journal of Surgical Pathology·Anne M MillsTeri A Longacre
Nov 2, 2014·Acta Cytologica·Alessia Di LoritoFernando Carlos Schmitt
Dec 3, 2015·Expert Opinion on Pharmacotherapy·Christopher de HayduAlessandro D Santin
Apr 26, 2016·Cytopathology : Official Journal of the British Society for Clinical Cytology·Y NorimatsuT K Kobayashi
Jun 20, 2016·Acta Cytologica·Güliz A BarkanDorothy L Rosenthal
Sep 23, 2016·Diagnostic Cytopathology·Niki MargariPetros Karakitsos
Feb 12, 2017·F1000Research·Arthur-Quan Tran, Paola Gehrig
Mar 6, 2017·Diagnostic Pathology·Wei ChenWendy L Frankel

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Citations

Oct 6, 2018·Cancer Science·Motoki MatsuuraTsuyoshi Saito
May 9, 2019·Cytopathology : Official Journal of the British Society for Clinical Cytology·Azusa NimuraTsutomu Tabata
Mar 19, 2021·Klinicheskaia laboratornaia diagnostika·A E KarpovaL B Tumgoeva
Sep 2, 2019·Acta Cytologica·Yoshiaki NorimatsuFranco Fulciniti
Oct 25, 2021·Cytopathology : Official Journal of the British Society for Clinical Cytology·Yoshiaki NorimatsuFranco Fulciniti
Nov 17, 2021·Diagnostic Cytopathology·Satoru Munakata, Toshiya Yamamoto

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