Theories of endometriosis

European Journal of Obstetrics, Gynecology, and Reproductive Biology
D VinatierP Dufour

Abstract

Endometriosis is characterised by the presence of abnormally located tissue resembling the endometrium with glands and stroma. Several hypotheses have attempted to explain the development of such tissue. The oldest theory, that of metaplasia, suggests that under diverse influences coelomic tissue could be transformed into endometrium. The most often cited theory, that of implantation, proposes that the physiological phenomenon of endometrial reflux in the fallopian tubes during menstruation may, in certain conditions, overcome local defense mechanisms, implant, and proliferate. The peritoneal fluid in unaffected women possesses the capacity to prevent endometriotic tissue from becoming established. The reasons for the occurrence of endometriosis and its consequences (pain, sterility, adhesions) are probably numerous and involve the endometrium, the immune system (macrophages, natural killer cells), the peritoneum, and fallopian tubes. The failure to clear the peritoneal cavity of fragments of endometrium could cause a state of local inflammation with hyperactivation of macrophages secreting a variety of different compounds. Some of these compounds may bring about metaplasia of the peritoneum or the development of Mullerian resi...Continue Reading

References

Oct 1, 1992·The Journal of Experimental Medicine·N JonjićA Mantovani
Oct 15, 1992·Biochemical and Biophysical Research Communications·K MatsumotoT Nakamura
Nov 1, 1992·Fertility and Sterility·M D SpuijbroekJ L Evers
Jul 1, 1992·American Journal of Obstetrics and Gynecology·H KanzakiT Mori
Jan 1, 1992·Gynecologic and Obstetric Investigation·E TanakaM Hiroi
Jul 1, 1991·American Journal of Obstetrics and Gynecology·S Fujii
Feb 1, 1991·Fertility and Sterility·R F KruitwagenR Rolland
Jun 1, 1990·Fertility and Sterility·M NisolleJ Donnez
Jan 1, 1989·Experimental Cell Biology·G Hunt
Jan 1, 1986·American Journal of Obstetrics and Gynecology·J S SanfilippoM A Yussman
May 1, 1980·American Journal of Obstetrics and Gynecology·S El-Mahgoub, S Yaseen
Jan 1, 1984·American Journal of Obstetrics and Gynecology·J HalmeR Wing
Mar 1, 1980·Obstetrics and Gynecology·D W DotyR C Winslow
Dec 1, 1980·European Journal of Obstetrics, Gynecology, and Reproductive Biology·R PunnonenV Nikkanen
Nov 1, 1980·British Journal of Obstetrics and Gynaecology·P R KoninckxI A Brosens
Dec 2, 1995·Lancet·R GaetjeA Starzinski-Powitz
Apr 22, 1994·Science·P C BrooksD A Cheresh
Aug 1, 1994·The Journal of Clinical Endocrinology and Metabolism·B A LesseyB L Strom
Aug 1, 1995·Fertility and Sterility·M WingfieldP A Rogers
Jun 1, 1995·Archives of Histology and Cytology·M YasudaY Tsutsumi
Aug 1, 1995·Proceedings of the National Academy of Sciences of the United States of America·K L BrunerK G Osteen
Jun 1, 1995·The Journal of Experimental Medicine·R Kolesnick, Z Fuks
Jan 1, 1995·Fertility and Sterility·S Fernández-ShawP M Starkey
Jan 1, 1994·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R GiavazziA J Gearing
Oct 11, 1994·Proceedings of the National Academy of Sciences of the United States of America·K G OsteenL M Matrisian
Aug 1, 1994·British Journal of Obstetrics and Gynaecology·J E BridgesE J Thomas

❮ Previous
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Citations

Aug 22, 2013·Journal of Minimally Invasive Gynecology·João Siufi NetoMaurício Simões Abrão
Mar 14, 2012·Skeletal Radiology·Vibhor WadhwaAvneesh Chhabra
May 2, 2012·Archives of Gynecology and Obstetrics·A AugouleaI Lambrinoudaki
Apr 19, 2013·Archives of Gynecology and Obstetrics·K DaliriH Derakhshankhah
Aug 1, 2008·The Indian Journal of Surgery·Rollings S Jamabo, Rosemary N Ogu
May 17, 2005·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Grzegorz B GmyrekAnna Chelmonska-Soyta
Dec 31, 2003·The Journal of Steroid Biochemistry and Molecular Biology·Kálmán A KovácsMarietta Vértes
Jul 10, 2012·Integrative Biology : Quantitative Biosciences From Nano to Macro·Zhenling ChenXingyu Jiang
Jun 2, 2011·Clinics in Colon and Rectal Surgery·Katrina Slaughter, Rajiv B Gala
Jun 7, 2013·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Lucy StephensMarie Polley
Jun 8, 2012·Human Reproduction·P HarirchianA T Fazleabas
Jun 7, 2008·Human Reproduction Update·Grant W MontgomeryKrina T Zondervan
May 30, 2008·Molecular Human Reproduction·S DefrèreA Van Langendonckt
Dec 20, 2012·The American Journal of Dermatopathology·Martina StojanovicMilan Stojicic
Jan 5, 2007·Gynecologic and Obstetric Investigation·Sun-Wei Guo, David L Olive
Apr 7, 2010·The Journal of Clinical Investigation·Hyunjung Jade Lim, Haibin Wang
Dec 28, 2010·Journal of Neurosurgery. Spine·John R FloydIan E McCutcheon
Jun 30, 2009·Journal of Human Reproductive Sciences·Ian S Fraser
Aug 8, 2014·The Permanente Journal·Parisa Azizad-Pinto, David Clarke
Jul 12, 2013·Obstetrics and Gynecology International·Antonio Simone LaganàOnofrio Triolo
Jul 21, 2007·Proceedings of the National Academy of Sciences of the United States of America·Aniko HeverAlbert Zlotnik
Sep 15, 2014·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Cláudia Maria da SilvaMárcia Mendonça Carneiro
Sep 6, 2014·Journal of Neurosurgery. Spine·Jeffrey A SteinbergJoseph D Ciacci
Jul 6, 2013·Women's Health·Marina Berbic, Ian S Fraser
Aug 28, 2012·Current Obstetrics and Gynecology Reports·Nilufer RahmiogluKrina T Zondervan
Oct 2, 2015·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Paula B T FettbackPaulo C Serafini
Sep 1, 2007·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·George ChristodoulakosGeorge Creatsas
Aug 31, 2011·Revista da Associação Médica Brasileira·Patrick BellelisMaurício Simões Abrão
Apr 9, 2013·Clinics and Research in Hepatology and Gastroenterology·Ahmed Fouad BourasPhilippe Zerbib
Jun 26, 2012·Neurocirugía·Miguel Domínguez-PáezMiguel Ángel Arráez-Sánchez
Jul 10, 2012·Journal de gynécologie, obstétrique et biologie de la reproduction·P VieilleR de Tayrac
May 23, 2012·Maturitas·Charlotte L Bendon, Christian M Becker
Oct 8, 2014·Taiwanese Journal of Obstetrics & Gynecology·Maurizio GuidaFulvio Zullo
Feb 5, 2010·Journal of Minimally Invasive Gynecology·Juan Gilabert-EstellesJuan Gilabert-Aguilar
Jun 9, 2009·Fertility and Sterility·Jae Sun ParkKi Hong Chang
Mar 13, 2009·Micron : the International Research and Review Journal for Microscopy·Plínio T BerardoLuiz E Nasciutti
Dec 27, 2008·Journal of Minimally Invasive Gynecology·Maurizio GuidaCarmine Nappi
Jan 11, 2007·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Agnete Fjerbaek, Ulla B Knudsen
Dec 4, 2003·Annals of the New York Academy of Sciences·P Moutsatsou, C E Sekeris
Jan 30, 2004·American Journal of Reproductive Immunology : AJRI·Ann-Muriel SteffDiane Gosselin

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