Therapeutic alternatives to surgical treatment of malignant eyelid tumors and their precursors

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
C GirbardtS Grunewald

Abstract

The treatment of choice for malignant eyelid tumors is surgical excision. If this is not feasible or undesirable, a number of alternative treatments are available. Possible systemic preparations are vismodegib and sonidegib for basal cell carcinoma as well as cetuximab and cemiplimab for squamous cell carcinoma. Cryodestruction is possible for superficial tumors. In situ findings can be treated with the local preparations imiquimod or 5‑fluorouracil and with photodynamic therapy. An interdisciplinary cooperation with dermatologists is advisable.

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