Therapeutic amniocentesis for treatment of twin-twin transfusion syndrome

Archives of Gynecology and Obstetrics
Recep HasLem'i Ibrahimoğlu

Abstract

The objective was to determine whether therapeutic amniocentesis may improve outcomes in patients with twin-twin transfusion syndrome. Eleven patients were managed aggressively with repetitive serial amniocenteses, and six patients were managed conservatively. The time interval between diagnosis and delivery was 17.4 days more in the amniodrainage group, but the difference between the groups was not significant (68.3+/-41.9 days in the therapeutic amniocentesis group and 50.83+/-29.7 days in the expectant management group [p=0.384]). The overall survival rate of the two groups was 38.2%, and was not significantly different between groups (40.9% in the amniocentesis group and 33.3% in the expectant management group; p=1.00). Two of nine (22.2%) infants in the amnioreduction group, and one of four (25.0%) infants in the expectantly managed group had neurological symptoms. Our results did not show a significant benefit of aggressive therapeutic amniocentesis. A slight improvement in perinatal outcome was observed.

References

Nov 1, 1986·American Journal of Obstetrics and Gynecology·B K WittmannL D Wadsworth
Aug 1, 1995·American Journal of Obstetrics and Gynecology·S J BowerN M Fisk
Jan 26, 1995·The New England Journal of Medicine·Y VilleK Nicolaides
Oct 1, 1993·American Journal of Obstetrics and Gynecology·D P ReisnerD A Luthy
Aug 1, 1997·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·N J SebireK H Nicolaides
May 1, 1997·Fetal Diagnosis and Therapy·J DeprestB J Hackeloër
Mar 24, 1998·Prenatal Diagnosis·K R DuncanN M Fisk
Jul 3, 1998·Fetal Diagnosis and Therapy·G R SaadeK J Moise
Mar 30, 2000·American Journal of Obstetrics and Gynecology·J E Dickinson, S F Evans
Jun 21, 2001·Archives of Gynecology and Obstetrics·S SuzukiT Araki

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Citations

Mar 13, 2020·Acta Obstetricia Et Gynecologica Scandinavica·Francesco D'AntonioAsma Khalil
Dec 19, 2020·Acta Obstetricia Et Gynecologica Scandinavica·Filomena Giulia SileoAsma Khalil

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