Therapeutic Application of Synbiotics, a Fusion of Probiotics and Prebiotics, and Biogenics as a New Concept for Oral Candida Infections: A Mini Review

Frontiers in Microbiology
Tomoko OhshimaNobuko Maeda

Abstract

Candida is a major human fungal pathogen causing infectious conditions predominantly in the elderly and immunocompromised hosts. Although Candida resides as a member of the oral indigenous microbiota in symbiosis, some circumstances may cause microbial imbalance leading to dysbiosis and resultant oral candidiasis. Therefore, oral microbial symbiosis that suppresses the overgrowth of Candida is important for a healthy oral ecosystem. In this regard, probiotics, prebiotics, and synbiotics can be considered a potential therapeutic and preventive strategy against oral candidiasis. Prebiotics have a direct effect on microbial growth as they stimulate the growth of beneficial bacteria and suppress the growth of pathogens. Probiotics render a local protective effect against pathogens and a systemic indirect effect on immunological amelioration. Synbiotics are fusion products of prebiotics and probiotics. This mini review discusses the potential use and associated limitations of probiotics, prebiotics, and synbiotics for the prevention and treatment of oral candidiasis. We will also introduce biogenics, a recent concept derived from the work on probiotics. Biogenics advocates the use of beneficial bioactive substances produced by probi...Continue Reading

References

Nov 1, 1977·The American Journal of Clinical Nutrition·T Mitsuoka, C Kaneuchi
Jan 1, 1976·Acta Odontologica Scandinavica·M LarmasA Scheinin
Nov 1, 1975·Journal of Dental Research·K K MäkinenH Vidgren
May 1, 1989·The Journal of Applied Bacteriology·R Fuller
Dec 1, 1988·Antimicrobial Agents and Chemotherapy·T L TalaricoW J Dobrogosz
Nov 1, 1972·Infection and Immunity·J Van HouteA J Pulkkinen
Mar 1, 1982·Canadian Journal of Microbiology·R Maleszka, H Schneider
Aug 1, 1981·Community Dentistry and Oral Epidemiology·C G Crossner
Sep 1, 1982·Applied and Environmental Microbiology·J M Jay
Jun 1, 1995·The Journal of Nutrition·G R Gibson, M B Roberfroid
Jan 1, 1994·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·C ScullyL P Samaranayake
Dec 16, 1998·The British Journal of Nutrition·S SalminenI Rowland
Sep 30, 2000·Applied and Environmental Microbiology·M G GänzleW P Hammes
Jul 4, 2001·Trends in Microbiology·R A Calderone, W A Fonzi
Jan 16, 2003·Trends in Microbiology·L Julia Douglas
Nov 1, 1960·Biochemical and Biophysical Research Communications·C CHIANG, S G KNIGHT
Feb 12, 1965·Science·D M LILLY, R H STILLWELL
Dec 4, 2003·The Lancet Infectious Diseases·Philippe EggimannDidier Pittet
Feb 1, 1952·Oral Surgery, Oral Medicine, and Oral Pathology·R L GLASS
Jan 16, 2007·Clinical Microbiology Reviews·M A Pfaller, D J Diekema
Feb 22, 2007·The Journal of Nutrition·Takeshi MatsuzakiTeruo Yokokura
Feb 19, 2008·Oral Microbiology and Immunology·P KõllL Hammarström
May 29, 2008·European Journal of Nutrition·Niels Peter MöllerJürgen Schrezenmeir
Jul 9, 2008·Journal of Pediatric Gastroenterology and Nutrition·Pinaki PanigrahiIra H Gewolb
Oct 31, 2009·Ageing Research Reviews·Kirsti TiihonenNina Rautonen
Jun 25, 2010·Journal of Microbiological Methods·R YangP W Caufield
Oct 6, 2010·BMC Genomics·Vladimir LazarevicJacques Schrenzel
Dec 15, 2010·International Journal of Cancer. Journal International Du Cancer·Johanna UittamoRiina Rautemaa
Jan 15, 2011·Journal of Leukocyte Biology·Pascal GourbeyreMarie Bodinier
Sep 8, 2012·Clinical Oral Investigations·Annica AlmståhlAnette Carlén

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Citations

Mar 24, 2018·British Dental Journal·G JiaL Ai
Jun 2, 2018·Current Medicinal Chemistry·Célia F RodriguesMariana C R Henriques
Apr 1, 2017·Clinical Drug Investigation·Leon Fisher, Alexander Fisher
Aug 14, 2020·PloS One·Mohammed Nadeem BijleCynthia Kar Yung Yiu
Apr 25, 2018·Probiotics and Antimicrobial Proteins·Meegun HongKi Tae Suk
Oct 1, 2020·Journal of Fungi·Lohith KunyeitReeta P Rao
Jun 15, 2019·BMC Oral Health·Shamsoulmolouk NajafiNarges Gholizadeh
Dec 17, 2018·Applied Microbiology and Biotechnology·Fernanda BianchiKatia Sivieri
Jul 30, 2019·Frontiers in Microbiology·Elena RosellettiAnna Vecchiarelli
Aug 23, 2016·World Journal of Gastroenterology : WJG·Hotaik SungKi Tae Suk
Oct 14, 2020·International Journal of Pharmaceutics·Cornelius C DodooSimon Gaisford
Jul 25, 2021·European Journal of Dentistry·Armelia Sari Widyarman, Citra Fragrantia Theodorea
May 2, 2018·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Yangheng ZhangFuhua Yan
Apr 5, 2019·Caries Research·Egija Zaura, Svante Twetman

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