Therapeutic applications of vasopressin in pediatric patients

Indian Pediatrics
Amit AgrawalRajesh Sharma

Abstract

Reports of successful use of vasopressin in various shock states and cardiac arrest has lead to the emergence of vasopressin therapy as a potentially major advancement in the management of critically ill children. To provide an overview of physiology of vasopressin, rationale of its use and dose schedule in different disease states with special focus on recent advances in the therapeutic applications of vasopressin. MEDLINE search (1966-September 2011) using terms vasopressin, terlipressin, arginine-vasopressin, shock, septic shock, vasodilatory shock, cardiac arrest, and resuscitation for reports on vasopressin/terlipressin use in children and manual review of article bibliographies. Search was restricted to human studies. Randomized controlled trials, cohort studies, evaluation studies, case series, and case reports on vasopressin/terlipressin use in children (preterm neonates to 21 years of age) were included. Outcome measures were analysed using following clinical questions: indication, dose and duration of vasopressin/terlipressin use, main effects especially on systemic blood pressure, catecholamine requirement, urine output, serum lactate, adverse effects, and mortality. 51 reports on vasopressin (30 reports) and terlipr...Continue Reading

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May 21, 2014·The Journal of Pediatrics·Shannon N AckerJason Gien
Sep 2, 2015·Revista chilena de pediatría·Daniela Arriagada SFranco Díaz R
Mar 13, 2013·Neonatal Network : NN·Michele J Beaulieu
Jan 2, 2019·Maternal Health, Neonatology and Perinatology·Katharina RufEric Frieauff

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