Therapeutic approach to Candida bezoar in children

Journal of Pediatric Urology
Liesbeth L de WallT P V M de Jong

Abstract

Candida bezoar (CB) is a rare finding in neonates and infants with candiduria, presenting as necrotic debris with proliferating mycelia in the collecting system of the kidney. If initial antifungal medical treatment does not result in clearance of candiduria and disappearance of CB on ultrasound in dilated kidneys, invasive interventions like insertion of nephrostomy tubes (NT) or surgical interventions to drain the kidney are sometimes advocated(.). However, NT placement can be a technical challenge, especially in pre- and dysmature neonates, and NT displacement or obstruction by the CB can lead to suboptimal treatment. Identification of those children who will benefit from invasive renal drainage is important. This study evaluates the management of patients with CB in three tertiary referral hospitals to determine criteria for intervention. A retrospective multicenter chart analysis was conducted of children with candiduria and ultrasonographic demonstration of CB (diagnosed between March 1995 and August 2012). The indication for invasive renal drainage (if performed) and subsequent clinical outcome, serum creatinine levels and ultrasound findings were assessed. A total of 12 children were included, two of which were prematur...Continue Reading

References

Nov 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M McDonnellD Isaacs
Feb 1, 1997·The Pediatric Infectious Disease Journal·J R Phillips, M G Karlowicz
Nov 5, 1999·Pediatrics·D K BenjaminD K Benjamin
Jul 1, 1963·The Journal of Pathology and Bacteriology·R HURLEY, H I WINNER
Oct 13, 2004·BJU International·Anni Eskild-JensenJørgen Frøkiaer
Nov 26, 2009·The Pediatric Infectious Disease Journal·Jennifer LeJay M Lieberman
Apr 9, 2010·Clinical Microbiology Reviews·Jacqueline M Achkar, Bettina C Fries
Nov 13, 2012·PloS One·Dhammika H M L P NavarathnaDavid D Roberts
May 3, 2013·Current Medical Research and Opinion·David Andes

❮ Previous
Next ❯

Citations

Feb 6, 2017·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Arend BokenkampHendricus J R van der Horst
Oct 12, 2018·Indian Journal of Pathology & Microbiology·Pradeep VaideeswarLamk Kadiyani
Mar 10, 2021·Journal of Paediatrics and Child Health·Jean FlanaganAlison Thomas

❮ Previous
Next ❯

Related Concepts

Related Feeds

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

AML: Role of LSD1 by CRISPR (Keystone)

Find the latest rersearrch on the ability of CRISPR-Cas9 mutagenesis to profile the interactions between lysine-specific histone demethylase 1 (LSD1) and chemical inhibitors in the context of acute myeloid leukemia (AML) here.

Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous disease with approximately 20,000 cases per year in the United States. AML also accounts for 15-20% of all childhood acute leukemias, while it is responsible for more than half of the leukemic deaths in these patients. Here is the latest research on this disease.