Therapeutic Approaches to Atrial Fibrillation Ablation Targeting Atrial Fibrosis

JACC. Clinical Electrophysiology
Hans KottkampAndreas Rieger

Abstract

Atrial fibrosis is the fundamental histopathologic finding in atrial fibrillation (AF) patients and an important predictor of ablation failure beyond pulmonary vein isolation. There is wide variation in the extent and localization of left atrial fibrosis in patients with paroxysmal and nonparoxysmal AF. Box isolation of fibrotic areas is an effective rhythm control concept in patients with paroxysmal AF despite durable pulmonary vein isolation, and this strategy has recently been implemented successfully in initial AF ablation procedures in addition to pulmonary vein isolation for patients with nonparoxysmal AF. In contrast, the time for "empirical" lines or other nonindividualized substrate modifications seems over.

References

Jul 28, 2007·Journal of Cardiovascular Electrophysiology·Koichiro KumagaiHideko Nakashima
Apr 4, 2009·Journal of the American College of Cardiology·Martin K StilesPrashanthan Sanders
Nov 15, 2011·Journal of the American College of Cardiology·Pyotr G PlatonovSiew Yen Ho
Oct 9, 2012·Journal of the American College of Cardiology·Michael F SwartzJosé Jalife
Dec 24, 2013·Circulation. Arrhythmia and Electrophysiology·Christopher McGannNassir F Marrouche
Jul 17, 2014·Circulation·Michel HaissaguerreRemi Dubois
Aug 26, 2014·Circulation. Arrhythmia and Electrophysiology·Sascha RolfChristopher Piorkowski
Dec 3, 2014·Journal of the American College of Cardiology·Rajeev K PathakPrashanthan Sanders
Jan 17, 2015·Journal of the American College of Cardiology·Hans KottkampJan Berg
Mar 21, 2015·Circulation. Arrhythmia and Electrophysiology·Elad AnterMark E Josephson
Aug 26, 2015·Journal of Cardiovascular Electrophysiology·Torsten KonradThomas Rostock
Oct 30, 2015·Journal of Cardiovascular Electrophysiology·Hans KottkampDoreen Schreiber
May 29, 2016·Journal of Cardiovascular Electrophysiology·Takanori YamaguchiNaohiko Takahashi
Nov 20, 2016·Journal of Cardiovascular Electrophysiology·Atsuhiko YagishitaMauricio Arruda

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Citations

Apr 3, 2019·Journal of Cardiovascular Electrophysiology·Michael GramlichPeter Seizer
Jan 31, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Anastasia XintarakouPanos Vardas
Oct 4, 2020·Journal of Clinical Medicine·Yong-Soo BaekYoung-Hoon Kim
Oct 22, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Andrea ChiocchiniAtul Verma
Feb 13, 2021·Journal of Cellular and Molecular Medicine·Jin MaShiyu Ma
Aug 10, 2020·Critical Pathways in Cardiology·Mohammad H AbbasiE Kevin Heist
Jun 15, 2021·Frontiers in Physiology·Marica MuffolettoOleg Aslanidi

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