Therapeutic Developments for Tics and Myoclonus

Movement Disorders : Official Journal of the Movement Disorder Society
Joseph Jankovic

Abstract

Tics and myoclonus are phenomenologically similar given that both are jerk-like movements, but, in contrast to myoclonus, tics are often preceded by premonitory sensations and are typically associated with a variety of behavioral comorbidities, including attention deficit and obsessive-compulsive disorder. There are many other clinical features that help differentiate these two hyperkinetic disorders. Whereas behavioral and antidopaminergic therapies are most effective in the management of tics, clonazepam, other anticonvulsants, and serotonergic drugs are often used to control myoclonic movements. Botulinum toxin may also be helpful in focal tics and in segmental forms of myoclonus. DBS plays an increasingly important role in the treatment of these disorders, particularly when they are generalized and are disabling despite optimal medical therapy.

References

Jan 31, 2013·Journal of Neural Transmission·Roji Thomas, Andrea E Cavanna
Feb 6, 2013·Toxicon : Official Journal of the International Society on Toxinology·Mark HallettJoseph Jankovic
Feb 13, 2013·Movement Disorders : Official Journal of the Movement Disorder Society·José Fidel Baizabal-CarvalloJoseph Jankovic
Apr 30, 2013·Indian Journal of Pediatrics·Shalini Sinha, Yogesh Kumar Sarin
May 18, 2013·Movement Disorders : Official Journal of the Movement Disorder Society·Lawrence ScahillJonathan W Mink
Aug 21, 2013·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Jose Felix Martí-MassóCoro Paisán-Ruiz
Sep 17, 2013·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·John N Caviness
Sep 18, 2013·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Roger M Kurlan
Oct 12, 2013·Handbook of Clinical Neurology·Philip A Starr
Oct 24, 2013·Movement Disorders : Official Journal of the Movement Disorder Society·Subhashie WijemanneJoseph Jankovic
Nov 15, 2013·The New England Journal of Medicine·Nora D Volkow, James M Swanson
Dec 4, 2013·International Review of Neurobiology·Sabine MogwitzVeit Roessner
Dec 4, 2013·International Review of Neurobiology·Andrea E Cavanna, Andrea Nani
Dec 4, 2013·International Review of Neurobiology·Cristiano TermineUmberto Balottin
Dec 18, 2013·Lancet Neurology·Neepa PatelMark Hallett
Jan 8, 2014·Movement Disorders : Official Journal of the Movement Disorder Society·Bella HuasenMonty Silverdale
Jan 9, 2014·Journal of Psychiatric Research·Joseph F McGuireEric A Storch
Jan 18, 2014·Clinical Neuropharmacology·Donald L GilbertRichard E Chipkin
Jan 18, 2014·Clinical Neuropharmacology·Lu Ye, Steven Lippmann
Jan 25, 2014·Movement Disorders : Official Journal of the Movement Disorder Society·Martje E van EgmondTom J de Koning
Feb 28, 2014·The New England Journal of Medicine·Heidi M Feldman, Michael I Reiff
Aug 15, 2014·The New England Journal of Medicine·Jon E Grant
Aug 27, 2014·Movement Disorders : Official Journal of the Movement Disorder Society·Joseph Jankovic, Raymund A C Roos
Oct 12, 2014·Neurology·Sandra M A van der SalmMarina A J Tijssen
Nov 16, 2014·Current Neurology and Neuroscience Reports·Kelly Mills, Zoltan Mari
Nov 20, 2014·Parkinsonism & Related Disorders·Angelo Y LucianoMark S LeDoux
Dec 6, 2014·Movement Disorders : Official Journal of the Movement Disorder Society·Lauren E SchrockUNKNOWN Tourette Syndrome Association International Deep Brain Stimulation (DBS) Database and Registry Study Group
Dec 10, 2014·Movement Disorders : Official Journal of the Movement Disorder Society·José Fidel Baizabal-CarvalloJoseph Jankovic
Dec 17, 2014·Journal of Neurology, Neurosurgery, and Psychiatry·José Fidel Baizabal-Carvallo, Joseph Jankovic
Jan 15, 2015·Journal of Paediatrics and Child Health·Daryl Efron
Jan 22, 2015·Brain & Development·Mark Hallett
Feb 5, 2015·Movement Disorders : Official Journal of the Movement Disorder Society·Benzi KlugerJoseph Jankovic
Feb 12, 2015·JAMA Psychiatry·Matthew E HirschtrittUNKNOWN Tourette Syndrome Association International Consortium for Genetics
Mar 20, 2015·Movement Disorders : Official Journal of the Movement Disorder Society·Emmanuel RozeDavid Grabli
Apr 18, 2015·Lancet Neurology·Joohi Jimenez-Shahed
Apr 29, 2015·Movement Disorders : Official Journal of the Movement Disorder Society·Drew S Kern, Anthony E Lang
Jun 11, 2015·Seminars in Neurology·Reetta Kälviäinen
Jun 20, 2015·Epilepsy Research·Peter WolfMatthias Koepp

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Citations

Feb 16, 2016·Progress in Neuro-psychopharmacology & Biological Psychiatry·Brent M KiousDavid R Shprecher
Oct 20, 2015·Movement Disorders : Official Journal of the Movement Disorder Society·Joseph JankovicUn Jung Kang
Jun 16, 2016·Lancet Neurology·Anne KoyLars Timmermann
Aug 29, 2016·Revue neurologique·E Apartis, L Vercueil
Dec 17, 2016·Expert Review of Neurotherapeutics·Stefano Caproni, Carlo Colosimo
Feb 27, 2016·F1000Research·Mary Ann Thenganatt, Joseph Jankovic
Mar 15, 2019·Clinical Neuropharmacology·Nicki Niemann, Joseph Jankovic
Jun 17, 2016·Current Opinion in Neurology·Christos Ganos
Sep 3, 2020·Journal of Child Neurology·Stephanie R KellerFlorian S Eichler
Nov 8, 2016·Expert Opinion on Pharmacotherapy·Joseph Jankovic
Jun 2, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Xueyu XuJingkai Gu
Oct 12, 2018·CNS Drugs·Arjun Tarakad, Joohi Jimenez-Shahed
Jan 20, 2020·Journal of Neural Transmission·Joseph Jankovic
Sep 11, 2017·Toxicon : Official Journal of the International Society on Toxinology·Joseph Jankovic
Nov 11, 2021·European Child & Adolescent Psychiatry·Veit RoessnerKerstin J Plessen

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